Is Acetaminophen and Codeine Phosphate the same as BENZHYDROCODONE AND ACETAMINOPHEN?

No. Acetaminophen and Codeine Phosphate (ACETAMINOPHEN AND CODEINE PHOSPHATE) and BENZHYDROCODONE AND ACETAMINOPHEN (BENZHYDROCODONE AND ACETAMINOPHEN) are distinct medications. They are sometimes confused because of similar branding or because they treat overlapping conditions, but they have different active ingredients and different safety profiles.

Which has fewer side effects, ACETAMINOPHEN AND CODEINE PHOSPHATE or BENZHYDROCODONE AND ACETAMINOPHEN?

Side-effect frequency varies by individual. The side-effect comparison section on this page shows FAERS-reported events for each drug side by side. FAERS is voluntary reporting, so it reflects what patients and clinicians chose to report, not absolute population risk.

Can I switch from ACETAMINOPHEN AND CODEINE PHOSPHATE to BENZHYDROCODONE AND ACETAMINOPHEN?

Switching medications should always be done under prescriber supervision. The "patient stories" section on this page includes accounts from people who have made the switch and what their transition felt like, but those are individual experiences, not protocols.

ACETAMINOPHEN AND CODEINE PHOSPHATE vs BENZHYDROCODONE AND ACETAMINOPHEN

Compare ACETAMINOPHEN AND CODEINE PHOSPHATE (Acetaminophen and Codeine Phosphate) and BENZHYDROCODONE AND ACETAMINOPHEN (Opioid Analgesic) — clinical data, side effects, and patient experiences.

ACETAMINOPHEN AND CODEINE PHOSPHATE

Acetaminophen and Codeine Phosphate, Codeine Linctus · Opioid Analgesic

How it works

Other agent

Approved for

INDICATIONS AND USAGE Acetaminophen and codeine phosphate tablets are indicated for the management of mild to moderate pain

where treatment with an opioid is appropriate and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction

abuse

misuse

OralTablet

BENZHYDROCODONE AND ACETAMINOPHEN

· Opioid Analgesic

How it works

12.1 Mechanism of Action Benzhydrocodone Benzhydrocodone is a prodrug of hydrocodone. Hydrocodone Hydrocodone is a full opioid agonist with relative selectivity for the mu-opioid r...

Approved for

abuse

and misuse with opioids

which can occur at any dosage or duration [see Warnings and Precautions ( 5.1 ) ] reserve APADAZ for use in patients for whom alternative treatment options [e.g.

non-opioid analgesics]: Have not been tolerated or are not expected to be tolerated

OralTablet

Quick Comparison

ACETAMINOPHEN AND CODEINE PHOSPHATEBENZHYDROCODONE AND ACETAMINOPHEN

Drug Class

Opioid Analgesic

Route

Oral

Half-Life

—

FDA Approved

—

Side Effect Frequency Comparison

Estimated frequency (%) based on clinical trial data

Side Effects

ACETAMINOPHEN AND CODEINE PHOSPHATE

Drug Not Working

1-10%

Fatigue

1-10%

Nausea

1-10%

Headache

1-10%

Diarrhea

1-10%

Shortness of Breath

1-10%

Joint Pain

1-10%

Vomiting

0.1-1%

BENZHYDROCODONE AND ACETAMINOPHEN

UTI

1-10%

Rash

1-10%

Condition Worsened

0.1-1%

Decreased Appetite

0.1-1%

Diarrhea

0.1-1%

Nausea

0.1-1%

FDA Warnings

ACETAMINOPHEN AND CODEINE PHOSPHATE

Assess each patient’s risk prior to prescribing acetaminophen and codeine phosphate tablets and monitor all patients regularly for the development of these behaviors and conditions [see WARNINGS]
Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression may occur with use of acetaminophen and codeine phosphate tablets, especially during initiation or following a dosage increase
To reduce the risk of respiratory depression, proper dosing and titration of Acetaminophen and codeine phosphate are essential [see Warnings]
Accidental Ingestion Accidental ingestion of even one dose of Acetaminophen and codeine phosphate tablets, especially by children, can result in a fatal overdose of acetaminophen and codeine phosphate [see WARNINGS]

BENZHYDROCODONE AND ACETAMINOPHEN

5 WARNINGS AND PRECAUTIONS Opioid-Induced Hyperalgesia and Allodynia : Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain
10 ) Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness : Monitor for sedation and respiratory depression
12 ) Serious Skin Reactions : Discontinue APADAZ immediately at the first appearance of skin rash and if symptoms associated with allergy or hypersensitivity occur
As an opioid, APADAZ exposes users to the risks of addiction, abuse, and misuse [see Drug Abuse and Dependence ( 9 ) ]

Community Sentiment Analysis

Based on 1 Reddit discussions

ACETAMINOPHEN AND CODEINE PHOSPHATE

positive

0 threads

BENZHYDROCODONE AND ACETAMINOPHEN

100%

positive

1 threads

Community Discussions

No community discussions found for ACETAMINOPHEN AND CODEINE PHOSPHATE yet.

Community Discussions

1 Reddit threads analysed for BENZHYDROCODONE AND ACETAMINOPHEN

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

5 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

KemPharm Confirms Receipt of $10 Million Milestone Payment for FDA Approval of AZSTARYS™ Per License Agreement with Affi…

CELEBRATION, Fla., April 21, 2021 (GLOBE NEWSWIRE) -- KemPharm, Inc. (NASDAQ:[KMPH](https://www.benzinga.com/stock/KMPH#NASDAQ)), a specialty pharmaceutical company engaged in the discovery and development of proprietary prodrugs, today announced receipt of a regulatory milestone payment of $10 mi

r/wallstreetbetsany505y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

ACETAMINOPHEN AND CODEINE PHOSPHATE vs BENZHYDROCODONE AND ACETAMINOPHEN: What You Should Know

Key Differences

Both ACETAMINOPHEN AND CODEINE PHOSPHATE and BENZHYDROCODONE AND ACETAMINOPHEN belong to the Opioid Analgesic class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients.

Shared Indications

Both medications are approved for abuse. When two drugs treat the same condition, the choice between them often depends on the patient's medical history, other medications, tolerability, and prescriber preference.

Safety Considerations

ACETAMINOPHEN AND CODEINE PHOSPHATE carries 4 FDA warnings. BENZHYDROCODONE AND ACETAMINOPHEN carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..

This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.

Related Comparisons

BENZHYDROCODONE AND ACETAMINOPHEN vs TRAMADOL HYDROCHLORIDE→BENZHYDROCODONE AND ACETAMINOPHEN vs CODEINE SULFATE→BENZHYDROCODONE AND ACETAMINOPHEN vs OXYCODONE HYDROCHLORIDE→BENZHYDROCODONE AND ACETAMINOPHEN vs OXYCODONE AND ACETAMINOPHEN→BENZHYDROCODONE AND ACETAMINOPHEN vs BUPRENORPHINE→BENZHYDROCODONE AND ACETAMINOPHEN vs BUPRENORPHINE AND NALOXONE→

Primary sources

Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.

ACETAMINOPHEN AND CODEINE PHOSPHATE: DailyMed label · FAERS adverse events · ClinicalTrials.gov
BENZHYDROCODONE AND ACETAMINOPHEN: DailyMed label · FAERS adverse events · ClinicalTrials.gov

Loading comparison data...

ACETAMINOPHEN AND CODEINE PHOSPHATE vs BENZHYDROCODONE AND ACETAMINOPHEN

Compare ACETAMINOPHEN AND CODEINE PHOSPHATE (Acetaminophen and Codeine Phosphate) and BENZHYDROCODONE AND ACETAMINOPHEN (Opioid Analgesic) — clinical data, side effects, and patient experiences.

ACETAMINOPHEN AND CODEINE PHOSPHATE

Acetaminophen and Codeine Phosphate, Codeine Linctus · Opioid Analgesic

How it works

Other agent

Approved for

INDICATIONS AND USAGE Acetaminophen and codeine phosphate tablets are indicated for the management of mild to moderate pain

where treatment with an opioid is appropriate and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction

abuse

misuse

OralTablet

BENZHYDROCODONE AND ACETAMINOPHEN

· Opioid Analgesic

How it works

12.1 Mechanism of Action Benzhydrocodone Benzhydrocodone is a prodrug of hydrocodone. Hydrocodone Hydrocodone is a full opioid agonist with relative selectivity for the mu-opioid r...

Approved for

abuse

and misuse with opioids

which can occur at any dosage or duration [see Warnings and Precautions ( 5.1 ) ] reserve APADAZ for use in patients for whom alternative treatment options [e.g.

non-opioid analgesics]: Have not been tolerated or are not expected to be tolerated

OralTablet

Quick Comparison

ACETAMINOPHEN AND CODEINE PHOSPHATEBENZHYDROCODONE AND ACETAMINOPHEN

Drug Class

Opioid Analgesic

Route

Oral

Half-Life

—

FDA Approved

—

Side Effect Frequency Comparison

Estimated frequency (%) based on clinical trial data

Side Effects

ACETAMINOPHEN AND CODEINE PHOSPHATE

Drug Not Working

1-10%

Fatigue

1-10%

Nausea

1-10%

Headache

1-10%

Diarrhea

1-10%

Shortness of Breath

1-10%

Joint Pain

1-10%

Vomiting

0.1-1%

BENZHYDROCODONE AND ACETAMINOPHEN

UTI

1-10%

Rash

1-10%

Condition Worsened

0.1-1%

Decreased Appetite

0.1-1%

Diarrhea

0.1-1%

Nausea

0.1-1%

FDA Warnings

ACETAMINOPHEN AND CODEINE PHOSPHATE

Assess each patient’s risk prior to prescribing acetaminophen and codeine phosphate tablets and monitor all patients regularly for the development of these behaviors and conditions [see WARNINGS]
Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression may occur with use of acetaminophen and codeine phosphate tablets, especially during initiation or following a dosage increase
To reduce the risk of respiratory depression, proper dosing and titration of Acetaminophen and codeine phosphate are essential [see Warnings]
Accidental Ingestion Accidental ingestion of even one dose of Acetaminophen and codeine phosphate tablets, especially by children, can result in a fatal overdose of acetaminophen and codeine phosphate [see WARNINGS]

BENZHYDROCODONE AND ACETAMINOPHEN

5 WARNINGS AND PRECAUTIONS Opioid-Induced Hyperalgesia and Allodynia : Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain
10 ) Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness : Monitor for sedation and respiratory depression
12 ) Serious Skin Reactions : Discontinue APADAZ immediately at the first appearance of skin rash and if symptoms associated with allergy or hypersensitivity occur
As an opioid, APADAZ exposes users to the risks of addiction, abuse, and misuse [see Drug Abuse and Dependence ( 9 ) ]

Community Sentiment Analysis

Based on 1 Reddit discussions

ACETAMINOPHEN AND CODEINE PHOSPHATE

positive

0 threads

BENZHYDROCODONE AND ACETAMINOPHEN

100%

positive

1 threads

Community Discussions

No community discussions found for ACETAMINOPHEN AND CODEINE PHOSPHATE yet.

Community Discussions

1 Reddit threads analysed for BENZHYDROCODONE AND ACETAMINOPHEN

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

5 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

KemPharm Confirms Receipt of $10 Million Milestone Payment for FDA Approval of AZSTARYS™ Per License Agreement with Affi…

r/wallstreetbetsany505y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

ACETAMINOPHEN AND CODEINE PHOSPHATE vs BENZHYDROCODONE AND ACETAMINOPHEN: What You Should Know

Key Differences

Shared Indications

Safety Considerations

This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.

Primary sources

Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.

ACETAMINOPHEN AND CODEINE PHOSPHATE: DailyMed label · FAERS adverse events · ClinicalTrials.gov
BENZHYDROCODONE AND ACETAMINOPHEN: DailyMed label · FAERS adverse events · ClinicalTrials.gov