Compare DULAGLUTIDE (TRULICITY) and Semaglutide (Ozempic) — clinical data, side effects, and patient experiences.
TRULICITY, Trulicity · GLP-1 Agonist
How it works
12.1 Mechanism of Action TRULICITY contains dulaglutide, which is a human GLP-1 receptor agonist with 90% amino acid sequence homology to endogenous human GLP-1 (7-37). Dulaglutide...
Approved for
Ozempic, Wegovy, Rybelsus · GLP-1 Agonist
How it works
Glucagon-like peptide-1 (GLP-1) receptor agonist with 94% homology to human GLP-1. Stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite c...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 23 Reddit discussions
DULAGLUTIDE
50%
positive
12 threads
Semaglutide
36%
positive
11 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for DULAGLUTIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
8 upvotes
Most discussed side effects in community
I mentioned in this thread about how Lilly was presenting retatrutide this summer. [https://www.reddit.com/r/Mounjaro/comments/14f9mqm/insurance\_stopped\_coverage\_and\_im\_feeling\_so\_low/](https://www.reddit.com/r/Mounjaro/comments/14f9mqm/insurance_stopped_coverage_and_im_feeling_so_low/) &
Just cloning his blog for convenience, direct link to [blog](http://martinshkreli.com/) Updated weekly(ish) \--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [10/10/18](ht
TLDR: A new analysis of SURPASS-CVOT finds tirzepatide is superior to dulaglutide in reducing cardio-renal events. This matters because dulaglutide has already been shown to reduce the incidence of cardiovascular events. ============================ SURPASS-CVOT looked at patients with type 2 diabet
[TRANSFORMING ALZHEIMER'S TREATMENT: INNOVATIVE COMBINATIONS TO BOOST COGNITION](https://preview.redd.it/4co071hgacsd1.png?width=1336&format=png&auto=webp&s=029945bb9c304ba2d1d4f06313a8ebf05ebf1aea) October 1, 2024 NetworkNewsWire Editorial Coverage: Alzheimer’s disease (“AD”) has become
hello friends,I’m a Chinese who plan to study in Canada.I have type 2 diabetes,and take GLP-1 drugs “Trulicity (Dulaglutide)”4 pens/mouth. I asked online and learned that 1 tube of it around 250 CAD,a mouth will be 1000 CAD,which is 8 times the price I used in China. I can’t afford it. I want to ask
The British Cardiovascular Society just published a detailed breakdown of the SURPASS-CVOT trial, which compared tirzepatide head-to-head against dulaglutide in over 13,000 patients with type 2 diabetes and established cardiovascular disease . Tirzepatide met the bar for noninferiority which means t
Hello ! I'm an agronomist engineer who works with data. My family is full of physicians, and growing up around medicine gave me a respect for the Hippocratic oath and a curiosity about drug safety. I started exploring FAERS (the FDA's adverse event reporting system, 30M+ spontaneous reports) and rea
I just started taking Trulicity today and am curious about other people's experiences with it. Has your A1C improved? Have you lost weight? Anything else notable about it? So far I feel like I'm less hungry, more full feeling; though that may just be placebo. Thank you to anywho who shares their ex
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
11 Reddit threads analysed for Semaglutide
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
30 upvotes
Most discussed side effects in community
I was diagnosed back at the end of March this year and I was very sick. My A1C was 14! Blood sugars of 300+ average. I took this very seriously as I had seen what type 1 did to my grandma. And I know type 1 and type 2 are two very different beasts, I did not want to have to give myself insulin as we
I am new diagnosed type 2 diabetic. My fasting bs was 140 and A1C is 6.4. My insurance denied both tirzepitide and Semaglutide brand names stating my A1C must be 6.5. I’m so frustrated. I had started taking compounded Semaglutide prior to my diagnosis for weight loss and then did my blood work and r
**1st June 2021 - new docs, start treatment** weight: **216 lb** / 97.98 kg height: 6'1" / 1.85 m BMI: 28.5 (overweight) BP: **132/90** (too high) *start lisinopril* HbA1c: **10.4%** average BG: 252 mg/dL, 14 mmol/L LDL: 127 mg/dL HDL: 36 mg/dL TG: 845 mg/dL (!)
I have been using ozempic for 3 months. My side effects were mild and bearable. I noticed that I got nausea when I ate unhealthy or large amounts of food. I started to eat less and better quality. I was more sensitive to motion nausea (like long bus rides), but all ok. Last month my period was
I was diagnosed with T2 in April 2024 after having symptoms like thirsty and weight loss . My A1C was 11.5 in April .after taking medications and vigorous workouts , A1C dropped to 5.5 in October . I trained for marathon and ran Chicago marathon . I put in lot of miles . I am not strict on diet tho
Well... I had a good run, but Ozempic has finally become Unobtainium where I live, and my endo seems intent on waiting a couple of days to get back to me to say that they sent a refill to a pharmacy that doesn't have it to sell. I'm supposed to take a 2 mg shot today, and my next endo appointment is
Hi guys, Happy New Year! I was diagnosed with T2 about a year ago, but I struggled taking care of myself. I was depressed and didn't really think about it too much, therefore, I was still eating a lot of junk food, staying all day in the couch but I was always feeling tired and my health wasn't the
Hi everyone. My husband (33) was recently diagnosed with type 2 diabetes and I am a feeling a broad mix of emotions. We got married this year, I'm a deeply anxious person, and it just made me jump straight to worst case scenarios. So it's been a hard couple of days and I don't think I'm making it an
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both DULAGLUTIDE and Semaglutide belong to the GLP-1 Agonist class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients. DULAGLUTIDE is administered via Subcutaneous, whereas Semaglutide uses Subcutaneous or Oral. Route of administration can affect onset of action and patient adherence.
DULAGLUTIDE carries 4 FDA warnings. Semaglutide carries 3 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.