Compare DULOXETINE (DULOXETINE HYDROCHLORIDE) and GABAPENTIN (Gabapentin) — clinical data, side effects, and patient experiences.
DULOXETINE HYDROCHLORIDE, Cymbalta · SNRI
How it works
12.1 Mechanism of Action Although the exact mechanisms of the antidepressant, central pain inhibitory and anxiolytic actions of duloxetine in humans are unknown, these actions are ...
Approved for
Gabapentin, Neurontin · Anticonvulsant
How it works
12.1 Mechanism of Action The precise mechanisms by which gabapentin produces its analgesic and antiepileptic actions are unknown. Gabapentin is structurally related to the neurotra...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 25 Reddit discussions
DULOXETINE
27%
positive
15 threads
GABAPENTIN
50%
positive
10 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for DULOXETINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
43 upvotes
Most discussed side effects in community
I am a 28 year old man and I've just realized that nothing interests me. I believe that it might be connected to depression as I am on medication for depression and anxiety (duloxetine) I am not really sad or anything. I am just very neutral. Things that used to interest, excite me and make me happ
I have been recovering from over a decade of major depressive disorder and recently diagnosed bipolar II. I’m seeing light at the end of the tunnel with Lamotrigine and lifestyle changes, and after several mental health evaluations, my psychiatrist gave me the best news ever; I can stop taking antid
Hi, just wondering if this is a common experience: So i've been taking agomelatine 50mg for about 5 months and duloxetine 60mg for 3 months now for severe depression and anxiety. The antidepressants have been working just as intended in the sense that most of the mental agony has gone, but there's
I ( M23) have been taking duloxetine 60 mg for 2 years now. While it has helped tremendously with my anxiety/depression/DPDR, it did cause sexual side effects for me. (I also take lamotrigine, but that is unlikely to cause effects like this) For me, these sides were very annoying; my main problem wa
Entry time 8:55am Before I went to sleep last night, I had nurses come 2 times, around 9:30pm and then at 10:40pm asking if I wanted to take some anxiety medication to help me sleep better. I refused both times as it wasn't initially prescribed, and in general I don't have a problem sleeping. My al
UHC is canceling coverage of my medication: Lamotrigine, Atomoxetine, and Duloxetine. Starts in January. Im barely getting by as it is. I need to find new insurance asap (Im in the USA). Its no wonder they were targeted. I just learned that they deny the most coverage of any US health insurer. Wtf a
Since the late of 2019 year, till now I've tried: 1- Escitalopram "Lexapro" (tried Atomoxetine "Strattera" with it, then stopped it due to its bad effects) (tried Risperidone "Rispardal" then stopped it, it hasn't only bad effects, but also highly increased prolactin) 2- Fluoxetine "Prozac" 3- Bupro
You know how a lot of sources say working towards a goal and then achieving it gives a sense of reward via dopamine? This week I got a pay rise, achieved a fitness goal I've been working towards for months and even got asked out on a date by someone quite attractive. But I feel absolutely nothing.
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
10 Reddit threads analysed for GABAPENTIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
391 upvotes
Most discussed side effects in community
I need to feel like I’m not crazy. I was diagnosed with fibro about two years ago. Underwent quite a few tests including an EMG to rule out other things. Currently taking gabapentin to help symptoms. But along with the pain I get so many muscle twitches. Kind of like when you get that really annoyi
Today my boyfriend of a year told me he doesn’t think I should be taking my opioid pain medication any longer. I have had chronic pain for 18 years, have tried every single thing I could think of, that was recommended to me, have had multiple surgeries, and ended up with CRPS in my right hip/thigh.
I'm going to share my story and what I've found does work and doesn't work for me. Feel free to ask questions. And feel free to comment with your own journey. I was diagnosed at 23. I went to Disney world and on the second day I woke up and couldn't walk. I was in so much pain. My legs and feet wer
And the only fibromyalgia drug in existence as far as any of them know is gabapentin, but gabapentin makes it so you can't feel your clitoris.
I had my monthly appointment with my PM doc this morning. I brought up the new drug that has just been approved by the FDA and wanted to get his thoughts on it. He said and I am quoting him pretty detailed here; The drug has only been approved by the FDA for acute pain only, as in post surgical pa
I work in a pharmacy, which is honestly an awful environment if you have chronic pain and fatigue because I'm absolutely killed after every shift, but honestly it's the attitudes of my coworkers that really cut deep. Right now, I'm not taking any opioid medication, but I did in the past and it's rea
So over 3 years ago now I had a very unpleasant situation occur with my pain doctor at the time. (The link to that long story is here: [https://www.reddit.com/r/ChronicPain/comments/xq86rj/an\_update\_to\_an\_arrogant\_doctor\_forcing\_me\_to\_go/](https://www.reddit.com/r/ChronicPain/comments/xq86r
I was hit by a fckn truck. I’m being as positive as I can be. She went on to say that she got better from her accident using positive thoughts and yoga. I wish I could do yoga. I’m in physical therapy with a goal of hopefully being able to do yoga again one day. No essential oil ointments don’t help
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
DULOXETINE is a SNRI, while GABAPENTIN belongs to the Anticonvulsant class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
DULOXETINE carries 4 FDA warnings. GABAPENTIN carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.