LEFLUNOMIDE vs USTEKINUMAB

In the UK it's known as Humira, Trudexa, Amgevita, Hyrimoz, Idacio, Imraldi and Yuflyma. After about two years on Methotrexate and one year on leflunomide I was really worried about starting Adalimumab. The other two drugs ravaged my body for a long time and made me feel like less of a person. They

RA is unapologetially kicking my ass both directly and indirectly lately. It makes my life so inconvenient in so many creative ways that it's almost funny. So to both vent some frustration and hopefully give you all a chuckle, here are some of the downright ridiculous things that are pushing me to t

Hey, just going to share my story as a warning for others. I’ve been on mtx for years, with good effect and usually prepare my meds in a dispense pack so I’m not getting a bunch of tabs out every morning. Ironically, a big part of the reason I do this is to minimise the risk of accidental incorrect

I’m honestly feeling lost and scared for my mom right now. She was diagnosed recently with seronegative rheumatoid arthritis after suffering from joint pain for almost a year. Her rheumatologist started her on the following medications: 1. Methotrexate 15 mg (once a week) 2. Folvite 5 mg (daily exce

I'm in SO MUCH PAIN right now. Preface. Ha. Saw rheumatologist yesterday for follow up. On Rinvoq & Leflunomide. Rinvoq isn't the miracle I'd hoped it would be but I'm so tired of switching meds and I need a break from injectables. Trying to make it work. Using Celebrex/celecoxib as needed. So r

hi yall! 23yrs, seropositive & 2.5 years into diagnosis here! this is my first real post in the sub! i wanted to share some positivity that has finally come my way!!! after cycling through a plethora of treatments - methotrexate (which put me in the er & resulted in nearly 70lbs of weight lo

Welcome back to this week's newsflash 1. Surgery for UC can be a major life change, but it is often a necessary step when medications fail. Understanding the adjustments to diet and daily life afterward is crucial for recovery and long-term well-being. This guide explores what patients can expect re

#The Effectiveness of Medications for Ulcerative Colitis *This post was last revised September 19, 2019.* Here I have compiled data on the effectiveness of medications used to treat ulcerative colitis, as compared to placebos or to other medications. ###Risk Ratios (RRs) All values here are shown as

Since eternacept started to wear off over the years my docs gave me the choice to switch to Ustekinumab. The 3 months injection rhythm sounds pretty unreal when coming from 3-day-interval Eternacept jabs, but well.. you could call it progress in medical science. I am now 3 weeks in after my first do

I wanted to follow-up on a previous post I made regarding starting Stelara. https://old.reddit.com/r/Psoriasis/comments/yjhr6z/plaque_psoriasis_after_a_covid_vaccine/ I have now be on Stelara for 7 months and it has nearly cleared my Psoriasis. I stopped applying Clobetasol some months ago and each

I’ve been on biologics for about a year now, i started in December 2024. About 45ml shot of Ustekinumab every 3 months as prescribed by my dermatologist. Problem is, it is losing its efficacy. Since August, every time it clears up about 70%, the same thing happens, it comes back worse even with topi

Phase 3 trials to commence. Possibly another biological option. http://www.medscape.com/viewarticle/878838

Sulforaphane Protects from T Cell–Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells [https://www.jimmunol.org/content/192/8/3530](https://www.jimmunol.org/content/192/8/3530) **Ustekinumab,** sold under the brand name **Stelara** is a [monoclonal antibody](https://en.wi

Hi everyone, i went through a lot of derms(atleast) from hand eczeme to funghus .. it is everything but nothing helps… my newest diagnose is pustulare psoriasis.. I aplied Winxory for 2weeks where my hands got „fine“ and then it happend again. my derm wants to put me on Ustekinumab?? just wante