How does ABACAVIR work?

ABACAVIR works through the following mechanism: 12.1 Mechanism of Action Abacavir is an antiretroviral agent [see Microbiology (12.4) ]..

What are the most common side effects of ABACAVIR?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for ABACAVIR. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is ABACAVIR the same as Abacavir?

Abacavir is a brand name for ABACAVIR. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

ABACAVIR

Q: What is ABACAVIR used for?

ABACAVIR (brand name Abacavir) is a Other indicated for 1 INDICATIONS AND USAGE Abacavir tablets, in combination with other antiretroviral agents, are indicated for the treatment of human immunodeficiency virus (HIV-1) infection. Abacavir tablets.

Other

Brand names: Abacavir

Oral

Mechanism of Action

12.1 Mechanism of Action Abacavir is an antiretroviral agent [see Microbiology (12.4) ].

Indications

1 INDICATIONS AND USAGE Abacavir tablets

in combination with other antiretroviral agents

are indicated for the treatment of human immunodeficiency virus (HIV-1) infection. Abacavir tablets

a nucleoside analogue human immunodeficiency virus (HIV-1) reverse transcriptase inhibitor

are indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. (1)

FDA Warnings

5 WARNINGS AND PRECAUTIONS Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues
1 Hypersensitivity Reactions Serious and sometimes fatal hypersensitivity reactions have occurred with abacavir
Patients who carry the HLA-B*5701 allele are at a higher risk of abacavir hypersensitivity reactions; although, patients who do not carry the HLA-B*5701 allele have developed hypersensitivity reactions
Due to the potential for severe, serious, and possibly fatal hypersensitivity reactions with abacavir: All patients should be screened for the HLA-B*5701 allele prior to initiating therapy with abacavir or reinitiation of therapy with abacavir, unless patients have a previously documented HLA-B*5701 allele assessment

Known Side Effects

8 documented side effects by frequency

Anxiety

1-10%

Fever

1-10%

Nausea

1-10%

Fatigue

1-10%

Rash

1-10%

Headache

1-10%

Vomiting

1-10%

High Blood Pressure

0.1-1%

Community Discussions

No community discussions found for ABACAVIR yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → ABACAVIR openFDA label JSON → ABACAVIR FAERS adverse-event reports → ABACAVIR ClinicalTrials.gov → completed Phase 2+ trials of ABACAVIR

Compare With

0 available comparisons

No comparisons yet.

Formulations

Dosage Forms

Tablet

Route

Oral