What are the most common side effects of ALFUZOSIN HYDROCHLORIDE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for ALFUZOSIN HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is ALFUZOSIN HYDROCHLORIDE the same as Alfuzosin Hydrochloride?

Alfuzosin Hydrochloride is a brand name for ALFUZOSIN HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

ALFUZOSIN HYDROCHLORIDE

Q: What is ALFUZOSIN HYDROCHLORIDE used for?

ALFUZOSIN HYDROCHLORIDE (brand name Alfuzosin Hydrochloride) is a Alpha Blocker indicated for 1 INDICATIONS AND USAGE Alfuzosin hydrochloride extended-release tablets, USP are indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. Alfuzosin hydrochloride extended-release tablet is an alpha adrenergic antagonist, 8.4.

Q: How does ALFUZOSIN HYDROCHLORIDE work?

ALFUZOSIN HYDROCHLORIDE works through the following mechanism: 12.1 Mechanism of Action Alfuzosin is a selective antagonist of post-synaptic alpha 1 -adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra..

Alpha Blocker

Brand names: Alfuzosin Hydrochloride

Oral

Mechanism of Action

12.1 Mechanism of Action Alfuzosin is a selective antagonist of post-synaptic alpha 1 -adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.

Indications

1 INDICATIONS AND USAGE Alfuzosin hydrochloride extended-release tablets

USP are indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. Alfuzosin hydrochloride extended-release tablet is an alpha adrenergic antagonist

8.4

12.3 ) 1.1 Important Limitations of Use Alfuzosin hydrochloride extended-release tablets

USP are not indicated for the treatment of hypertension. Alfuzosin hydrochloride extended-release tablets

USP are not indicated for use in the pediatric population.

Contraindications

• 4 CONTRAINDICATIONS Alfuzosin hydrochloride extended-release tablets are contraindicated for use: in patients with moderate or severe hepatic impairment (Childs-Pugh categories B and C)
• since alfuzosin blood levels are increased in these patients [ see Use in Specific Populations ( 8.7 ) and Clinical Pharmacology ( 12.3) ]. with potent CYP3A4 inhibitors such as ketoconazole
• itraconazole
• and ritonavir
• since alfuzosin blood levels are increased [ see Drug Interactions ( 7.1 ) and Clinical Pharmacology ( 12.3 ) ]. in patients with known hypersensitivity

FDA Warnings

5 WARNINGS AND PRECAUTIONS Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5
There may be an increased risk of hypotension/postural hypotension and syncope when taking alfuzosin hydrochloride extended-release tablets concomitantly with anti-hypertensive medication and nitrates
3 Patients with Hepatic Impairment Alfuzosin hydrochloride extended-release tablets are contraindicated for use in patients with moderate or severe hepatic impairment [ see Contraindications ( 4 ), Use in Specific Populations ( 8
4 Drug-Drug Interactions Potent CYP3A4 Inhibitors Alfuzosin hydrochloride extended-release tablets are contraindicated for use with potent CYP3A4 inhibitors (e

Known Side Effects

11 documented side effects by frequency

Dizziness

>10%

Drug Not Working

>10%

Fatigue

1-10%

Shortness of Breath

1-10%

Weakness

1-10%

Diarrhea

1-10%

Falls

1-10%

Nausea

1-10%

Low Blood Pressure

1-10%

Headache

1-10%

General Unwellness

0.1-1%

Community Discussions

No community discussions found for ALFUZOSIN HYDROCHLORIDE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → ALFUZOSIN HYDROCHLORIDE openFDA label JSON → ALFUZOSIN HYDROCHLORIDE FAERS adverse-event reports → ALFUZOSIN HYDROCHLORIDE ClinicalTrials.gov → completed Phase 2+ trials of ALFUZOSIN HYDROCHLORIDE

Compare With

6 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral