Question 1

What is BICALUTAMIDE used for?

Accepted Answer

BICALUTAMIDE (brand name bicalutamide) is a Other indicated for 1 INDICATIONS AND USAGE Bicalutamide tablets.

Question 2

How does BICALUTAMIDE work?

Accepted Answer

BICALUTAMIDE works through the following mechanism: 12.1 Mechanism of Action Bicalutamide is a non-steroidal androgen receptor inhibitor. It competitively inhibits the action of androgens by binding to cytosol androgen receptors in the target tissue. Prostatic carcinoma is known to be androgen sensitive and responds to treatment that counteracts the effect of androgen and/or removes the source of androgen. When bicalutamide is combined with LHRH analog therapy, the suppression of serum testosterone induced by the LHRH analog is not affected. However, in clinical trials with bicalutamide as a single agent for prostate cancer, rises in serum testosterone and estradiol have been noted. In a subset of patients who have been treated with bicalutamide and an LHRH agonist, and who discontinue bicalutamide therapy due to progressive advanced prostate cancer, a reduction in Prostate Specific Antigen (PSA) and/or clinical improvement (antiandrogen withdrawal phenomenon) may be observed..

Question 3

What are the most common side effects of BICALUTAMIDE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for BICALUTAMIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is BICALUTAMIDE the same as bicalutamide?

Accepted Answer

bicalutamide is a brand name for BICALUTAMIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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