What is BUTAL used for?

BUTAL (brand name BUTAL/APAP/CAFFEINE) is a CNS Stimulant indicated for Butalbital.

BUTAL works through the following mechanism: CNS Stimulant agent.

What are the most common side effects of BUTAL?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for BUTAL. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is BUTAL the same as BUTAL/APAP/CAFFEINE?

BUTAL/APAP/CAFFEINE is a brand name for BUTAL. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

BUTAL

CNS Stimulant

Brand names: BUTAL/APAP/CAFFEINE

Oral

Mechanism of Action

CNS Stimulant agent

Indications

Butalbital

Contraindications

• This product is contraindicated under the following conditions: – Hypersensitivity or intolerance to any component of this product – Patients with porphyria.

FDA Warnings

Hepatotoxicity - Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death
BOXED WARNING Hepatotoxicity Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death

Known Side Effects

0 documented side effects by frequency

No structured side effect data available.

Community Discussions

4 Reddit threads analysed for BUTAL

Overall Sentiment

Mixed

Comparison Threads

Avg Post Score

2 upvotes

Most discussed side effects in community

Nausea (2)

Headache (1)

Muscle Pain (1)

Appetite Changes (1)

Constipation (1)

Fatigue (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

Sever headache for seven days straight, now above left eyebrow and behind left eye.

F/27/NC/115 lbs/ 5’4” I have had a severe headache for seven days, constant non stop. Tylenol, ibuprofen, mucinex, cold medicine, naproxen does not help even one bit. I went to the ER and they told me it was a sinus infection and it will run it’s course. The gave me butal/acte/caff tabs and the d

r/AskDocs346y ago

Nausea

Headache

Muscle Pain

Serotonin Syndrome or just a migraine?

23F 5'4 117lbs. Diagnosed with MDD, GAD, BPD, ASD, DIE and chronic migraines. Currently taking paxil 10mg (began taking the night of 9/11/25), junel fe (unsure of dosage, birth control), xanax 0.5mg 1-2 a day PRN, and butal-asa-caff (also unsure of dosage). I had just been on Pristiq 25mg and stoppe

r/AskDocs118mo ago

Constipation

Is it all in my head?

36F conscious, alert, breathing normally / dx migraines with and without aura, acute stress disorder hx parasthesia, muscle spasms, vertigo, nausea / rx verapamil for migraine prevention and tachycardia ; butal-asa-caff cap as needed for migraines ; hydroxyzine as needed for anxiety ; (new, see:mysc

r/AskDocs113y ago

Nausea

Fatigue

Anxiety

Started Off With High ALP But Now What?

Age: 31 Sex: Female Height: 5 ft 5 inches Weight: 180 lbs Location: United States (Texas) Existing Conditions: Depression, GAD, HBP, Migraines, Hypothyroidism Duration: 3 years Race: White Current Medications: (I don’t remember all of them at the moments but the ones I can recall are:) Wellbutrin XL

r/AskDocs117y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → BUTAL openFDA label JSON → BUTAL FAERS adverse-event reports → BUTAL ClinicalTrials.gov → completed Phase 2+ trials of BUTAL

Compare With

14 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral