What is CABOTEGRAVIR used for?

CABOTEGRAVIR (brand name Apretude) is a Other indicated for 2.4 ), Contraindications ( 4 ).

What are the most common side effects of CABOTEGRAVIR?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for CABOTEGRAVIR. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is CABOTEGRAVIR the same as Apretude?

Apretude is a brand name for CABOTEGRAVIR. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

CABOTEGRAVIR

Q: How does CABOTEGRAVIR work?

CABOTEGRAVIR works through the following mechanism: 12.1 Mechanism of Action Cabotegravir is an HIV-1 antiretroviral drug [see Microbiology ( 12.4 )] in a long-acting formulation..

Other

Brand names: Apretude

Oral

Mechanism of Action

12.1 Mechanism of Action Cabotegravir is an HIV-1 antiretroviral drug [see Microbiology ( 12.4 )] in a long-acting formulation.

Indications

2.4 )

Contraindications ( 4 )

Contraindications

• 4 CONTRAINDICATIONS APRETUDE is contraindicated in individuals: • with unknown or positive HIV-1 status [see Warnings and Precautions ( 5.1
• which may result in reduced effectiveness [see Drug Interactions ( 7.2
• 7.3 )
• Clinical Pharmacology ( 12.3 )] : o Anticonvulsants: Carbamazepine
• oxcarbazepine

FDA Warnings

5 WARNINGS AND PRECAUTIONS • Comprehensive management to reduce the risk of HIV-1 acquisition
1 ) • Potential risk of developing resistance to APRETUDE if an individual acquires HIV-1 either before or while taking APRETUDE or following discontinuation of APRETUDE
Reassess risk of HIV-1 acquisition and test before each injection to confirm HIV-1 negative status
3 ) • Serious or severe hypersensitivity reactions have been reported with cabotegravir and include Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN)

Known Side Effects

3 documented side effects by frequency

Injection Site Pain

>10%

Fever

0.1-1%

Fatigue

0.1-1%

Community Discussions

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Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → CABOTEGRAVIR openFDA label JSON → CABOTEGRAVIR FAERS adverse-event reports → CABOTEGRAVIR ClinicalTrials.gov → completed Phase 2+ trials of CABOTEGRAVIR

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Formulations

Dosage Forms

Tablet

Route

Oral