Question 1

What is CAPLACIZUMAB used for?

Accepted Answer

CAPLACIZUMAB (brand name Cablivi) is a Other indicated for 1 INDICATIONS AND USAGE CABLIVI is indicated for the treatment of adult and pediatric patients 12 years of age and older with acquired thrombotic thrombocytopenic purpura (aTTP), in combination with plasma exchange and immunosuppressive therapy. ( 1 ).

Question 2

How does CAPLACIZUMAB work?

Accepted Answer

CAPLACIZUMAB works through the following mechanism: 12.1 Mechanism of Action Caplacizumab-yhdp targets the A1-domain of vWF, and inhibits the interaction between vWF and platelets, thereby reducing both vWF-mediated platelet adhesion and platelet consumption..

Question 3

What are the most common side effects of CAPLACIZUMAB?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for CAPLACIZUMAB. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is CAPLACIZUMAB the same as Cablivi?

Accepted Answer

Cablivi is a brand name for CAPLACIZUMAB. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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