Question 1

What is CIDOFOVIR ANHYDROUS used for?

Accepted Answer

CIDOFOVIR ANHYDROUS (brand name CIDOFOVIR) is a Other indicated for CONGENITAL OR NEONATAL CMV DISEASE, OR CMV DISEASE IN NON-HIV-INFECTED INDIVIDUALS..

Question 2

How does CIDOFOVIR ANHYDROUS work?

Accepted Answer

CIDOFOVIR ANHYDROUS works through the following mechanism: Mechanism of Action Cidofovir suppresses cytomegalovirus (CMV) replication by selective inhibition of viral DNA synthesis. Biochemical data support selective inhibition of CMV DNA polymerase by cidofovir diphosphate, the active intracellular metabolite of cidofovir. Cidofovir diphosphate inhibits herpesvirus polymerases at concentrations that are 8- to 600-fold lower than those needed to inhibit human cellular DNA polymerases alpha, beta, and gamma 1, 2, 3 . Incorporation of cidofovir into the growing viral DNA chain results in reductions in the rate of viral DNA synthesis..

Question 3

What are the most common side effects of CIDOFOVIR ANHYDROUS?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for CIDOFOVIR ANHYDROUS. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is CIDOFOVIR ANHYDROUS the same as CIDOFOVIR?

Accepted Answer

CIDOFOVIR is a brand name for CIDOFOVIR ANHYDROUS. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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