Question 1

What is CINACALCET used for?

Accepted Answer

CINACALCET (brand name CINACALCET) is a Other indicated for but who are unable to undergo parathyroidectomy. [see Clinical Studies ( 14.3 )] ..

Question 2

How does CINACALCET work?

Accepted Answer

CINACALCET works through the following mechanism: 12.1 Mechanism of Action The calcium-sensing receptor on the surface of the chief cell of the parathyroid gland is the principal regulator of PTH synthesis and secretion. Cinacalcet, the active ingredient in cinacalcet tablets is a calcimimetic agent that directly lowers PTH levels by increasing the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. The reduction in PTH is associated with a concomitant decrease in serum calcium levels..

Question 3

What are the most common side effects of CINACALCET?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for CINACALCET. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is CINACALCET the same as CINACALCET?

Accepted Answer

CINACALCET is a brand name for CINACALCET. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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