How does CLOMIPRAMINE HYDROCHLORIDE work?

CLOMIPRAMINE HYDROCHLORIDE works through the following mechanism: Other agent.

What are the most common side effects of CLOMIPRAMINE HYDROCHLORIDE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for CLOMIPRAMINE HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is CLOMIPRAMINE HYDROCHLORIDE the same as CLOMIPRAMINE HYDROCHLORIDE?

CLOMIPRAMINE HYDROCHLORIDE is a brand name for CLOMIPRAMINE HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

CLOMIPRAMINE HYDROCHLORIDE

Q: What is CLOMIPRAMINE HYDROCHLORIDE used for?

CLOMIPRAMINE HYDROCHLORIDE (brand name CLOMIPRAMINE HYDROCHLORIDE) is a Tricyclic Antidepressant indicated for INDICATIONS AND USAGE Clomipramine hydrochloride capsules, USP is indicated for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). The obsessions or compulsions must cause marked distress, be time-consuming.

Tricyclic Antidepressant

Brand names: CLOMIPRAMINE HYDROCHLORIDE

Oral

Mechanism of Action

Other agent

Indications

INDICATIONS AND USAGE Clomipramine hydrochloride capsules

USP is indicated for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). The obsessions or compulsions must cause marked distress

be time-consuming

or significantly interfere with social or occupational functioning

in order to meet the DSM-III-R (circa 1989) diagnosis of OCD. Obsessions are recurrent

persistent ideas

Contraindications

• CONTRAINDICATIONS Clomipramine hydrochloride capsules
• USP are contraindicated in patients with a history of hypersensitivity to clomipramine hydrochloride capsules
• USP or other tricyclic antidepressants. Monoamine Oxidase Inhibitors (MAOIs) The use of MAOIs intended to treat psychiatric disorders with clomipramine hydrochloride capsules
• USP or within 14 days of stopping treatment with clomipramine hydrochloride capsules
• USP are contraindicated because of an increased risk of serotonin syndrome. The use of clomipramine hydrochloride capsules

FDA Warnings

Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders
Anyone considering the use of clomipramine hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need
Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide

Known Side Effects

9 documented side effects by frequency

Drowsiness

1-10%

Falls

1-10%

Tremor

1-10%

Nausea

1-10%

Drug Not Working

1-10%

Anxiety

1-10%

Depression

1-10%

General Unwellness

1-10%

Rapid Heart Rate

1-10%

Community Discussions

1 Reddit threads analysed for CLOMIPRAMINE HYDROCHLORIDE

Overall Sentiment

Slightly negative

Comparison Threads

Avg Post Score

1 upvotes

Most discussed side effects in community

Headache (1)

Muscle Pain (1)

Anxiety (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

Vision getting darker suddenly, then back to normal

Hi, I'm 23,ftm, 1.73 m tall, 130 kg, Caucasian, non smoker, rarely use alcohol or weed, never anything stronger unless prescribed by a doctor. Diagnosed with OCD, PTSD, major depressive episodes, anxiety. Also diagnosed with scheuermann's disease, kyphosis, scoliosis, migraines, epilepsy (is new and

r/AskDocs111y ago

Headache

Muscle Pain

Anxiety

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → CLOMIPRAMINE HYDROCHLORIDE openFDA label JSON → CLOMIPRAMINE HYDROCHLORIDE FAERS adverse-event reports → CLOMIPRAMINE HYDROCHLORIDE ClinicalTrials.gov → completed Phase 2+ trials of CLOMIPRAMINE HYDROCHLORIDE

Compare With

12 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral