How does DARUNAVIR work?

DARUNAVIR works through the following mechanism: 12.1 Mechanism of Action Darunavir is an HIV-1 antiviral drug [see Microbiology ( 12.4 )] ..

What are the most common side effects of DARUNAVIR?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for DARUNAVIR. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is DARUNAVIR the same as Darunavir?

Darunavir is a brand name for DARUNAVIR. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

DARUNAVIR

Q: What is DARUNAVIR used for?

DARUNAVIR (brand name Darunavir) is a Other indicated for 1 INDICATIONS AND USAGE Darunavir, co-administered with ritonavir (darunavir/ritonavir), in combination with other antiretroviral agents.

Other

Brand names: Darunavir, PREZCOBIX

Oral

Mechanism of Action

12.1 Mechanism of Action Darunavir is an HIV-1 antiviral drug [see Microbiology ( 12.4 )] .

Indications

1 INDICATIONS AND USAGE Darunavir

co-administered with ritonavir (darunavir/ritonavir)

in combination with other antiretroviral agents

Contraindications

• please refer to ritonavir prescribing information for a description of ritonavir contraindications. Alpha 1-adrenoreceptor antagonist: alfuzosin Anti-gout: colchicine
• in patients with renal and/or hepatic impairment Antimycobacterial: rifampin Antipsychotics: lurasidone
• pimozide Cardiac Disorders: dronedarone
• ivabradine
• ranolazine Ergot derivatives

FDA Warnings

5 WARNINGS AND PRECAUTIONS Drug-induced hepatitis (e
Post-marketing cases of liver injury, including some fatalities, have been reported
Patients with pre-existing liver dysfunction, including chronic active hepatitis B or C, have an increased risk for liver function abnormalities including severe hepatic adverse events
Post-marketing cases of liver injury, including some fatalities, have been reported

Known Side Effects

1 documented side effects by frequency

Anxiety

1-10%

Community Discussions

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Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → DARUNAVIR openFDA label JSON → DARUNAVIR FAERS adverse-event reports → DARUNAVIR ClinicalTrials.gov → completed Phase 2+ trials of DARUNAVIR

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Formulations

Dosage Forms

Tablet

Route

Oral