What is DIAZOXIDE CHOLINE used for?

DIAZOXIDE CHOLINE (brand name VYKAT XR) is a Other indicated for See full prescribing information.

What are the most common side effects of DIAZOXIDE CHOLINE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for DIAZOXIDE CHOLINE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is DIAZOXIDE CHOLINE the same as VYKAT XR?

VYKAT XR is a brand name for DIAZOXIDE CHOLINE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

DIAZOXIDE CHOLINE

Q: How does DIAZOXIDE CHOLINE work?

DIAZOXIDE CHOLINE works through the following mechanism: 12.1 Mechanism of Action The exact mechanism of action of diazoxide choline in the treatment of hyperphagia in patients 4 years of age and older with Prader-Willi syndrome (PWS) is unknown..

Other

Brand names: VYKAT XR

Oral

Mechanism of Action

12.1 Mechanism of Action The exact mechanism of action of diazoxide choline in the treatment of hyperphagia in patients 4 years of age and older with Prader-Willi syndrome (PWS) is unknown.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS VYKAT XR is contraindicated in patients with known hypersensitivity to diazoxide
• other components of VYKAT XR
• or to thiazides. Erythema multiforme has been reported with VYKAT XR [see Adverse Reactions (6) ] . Known hypersensitivity to diazoxide
• other components of VYKAT XR
• or to thiazides. ( 4 )

FDA Warnings

5 WARNINGS AND PRECAUTIONS Hyperglycemia : Hyperglycemia, including diabetic ketoacidosis, has been reported
Monitor fasting glucose more frequently during first few weeks of treatment in patients with risk factors for hyperglycemia
1 ) Risk of Fluid Overload : Edema, including severe reactions associated with fluid overload, has been reported
Monitor fasting glucose more frequently for the first few weeks of treatment with VYKAT XR in patients with risk factors for hyperglycemia, such as obesity, elevated FPG, HbA1c at the upper limit of normal or above, concomitant use of growth hormone, or concomitant use of systemic corticosteroids

Known Side Effects

4 documented side effects by frequency

Drug Not Working

>10%

Peripheral Edema

1-10%

Weight Gain

0.1-1%

Shortness of Breath

0.1-1%

Community Discussions

No community discussions found for DIAZOXIDE CHOLINE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → DIAZOXIDE CHOLINE openFDA label JSON → DIAZOXIDE CHOLINE FAERS adverse-event reports → DIAZOXIDE CHOLINE ClinicalTrials.gov → completed Phase 2+ trials of DIAZOXIDE CHOLINE

Compare With

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Formulations

Dosage Forms

Tablet

Route

Oral