What is DULOXETINE D used for?

DULOXETINE D (brand name Duloxetine D/R) is a SNRI indicated for See full prescribing information.

How does DULOXETINE D work?

DULOXETINE D works through the following mechanism: Other agent.

What are the most common side effects of DULOXETINE D?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for DULOXETINE D. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is DULOXETINE D the same as Duloxetine D/R?

Duloxetine D/R is a brand name for DULOXETINE D. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

DULOXETINE D

SNRI

Brand names: Duloxetine D/R

Oral

Mechanism of Action

Other agent

Indications

See full prescribing information

FDA Warnings

1 Suicidal Thoughts and Behaviors in Children, Adolescents, and Young Adults Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs
Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide
Pooled analyses of short-term placebo-controlled trials of antidepressant drugs (SSRIs and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (ages 18 to 24) with major depressive disorder (MDD) and other psychiatric disorders
Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction with antidepressants compared to placebo in adults aged 65 and older

Known Side Effects

12 documented side effects by frequency

Nausea

>10%

Fatigue

1-10%

Drug Not Working

1-10%

Headache

1-10%

Dizziness

1-10%

Diarrhea

1-10%

Insomnia

1-10%

Anxiety

1-10%

Vomiting

1-10%

Depression

1-10%

Falls

0.1-1%

Tingling/Numbness

0.1-1%

Community Discussions

2 Reddit threads analysed for DULOXETINE D

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

58,428 upvotes

Most discussed side effects in community

Sexual Dysfunction (1)

Mood Changes (1)

Cough (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

My son is a hateful incel, and I just cannot save him or defend him anymore.

My boy, my oldest child, was so good when he was little, but something broke inside of him when he was a teenager. My wife and I always accepted, loved, and encouraged him. We pushed him to work hard and treat people with respect. I don’t know where exactly we failed him but as a father I feel resp

r/self58,75486157y ago

Sexual Dysfunction

Mood Changes

LPT: When your loved one is close to the end be aware that in most cases it isn’t the peaceful way it’s depicted in movi…

For most here this probably won’t be something you deal with more then a handful of times in your life. Which is why I think it’s important to know what your potentially walking into and the shit that follows you afterwards. I lost my dad three years ago to lymphoma/complications from it. Ive watch

r/LifeProTips58,10227693y ago

Cough

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → DULOXETINE D openFDA label JSON → DULOXETINE D FAERS adverse-event reports → DULOXETINE D ClinicalTrials.gov → completed Phase 2+ trials of DULOXETINE D

Compare With

10 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral