Brand names: eletriptan hydrobromide
12.1 Mechanism of Action Eletriptan binds with high affinity to 5-HT 1B , 5-HT 1D and 5-HT 1F receptors, has modest affinity for 5-HT 1A , 5-HT 1E , 5-HT 2B and 5-HT 7 receptors. Migraines are likely due to local cranial vasodilatation and/or to the release of sensory neuropeptides (vasoactive intestinal peptide, substance P and calcitonin gene-related peptide) through nerve endings in the trigeminal system. The therapeutic activity of eletriptan hydrobromide tablets for the treatment of migraine headache is thought to be due to the agonist effects at the 5-HT 1B/1D receptors on intracranial blood vessels (including the arterio-venous anastomoses) and sensory nerves of the trigeminal system which result in cranial vessel constriction and inhibition of pro-inflammatory neuropeptide release.
Contraindications
11 documented side effects by frequency
5 Reddit threads analysed for ELETRIPTAN HYDROBROMIDE
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Mixed
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121 upvotes
Most discussed side effects in community
Hey folks, Six weeks ago, I underwent "migraine surgery," by Dr. Day at the Pacific Sound Plastic Surgery. It was the most amazing thing that has ever happened to me, and I wanted to share my experience in case there are others like me out there. **My headaches** I'm 39M, and I've had a constant hea
I (22f) went to the mayo clinic today in scottsdale to see a headache specialist neurologist and it was the WORST experience ever. For context, I’ve had average 22 migraines a month for the past 3 years. When they started in 2019, I would get average like 3 a month. They are debilitating, I’m on Qul
Fellow Migraineurs: I have chronic migraines. If I wasn't on emgality, I would have migraines every day. I have a migraine specialist neurologist, I'm a 30 year old woman and I have had my mri's done, as well as a CT scan. I realize that I have never actually met anyone else in my whole life who has
I see a lot of folks complaining about side effects here and want to share what I've learned. This is a long info-dump; feel free to skip around for parts that are most relevant to you, but DO NOT skip the following disclaimer: **Disclaimer**: I am not a doctor or medical practitioner. I'm just a ve
I’ve had chronic migraine for 6 months, been treating it with meds and lifestyle changes for 3 months. When I start to feel my headache progress, I’ll take a triptan (rizatriptan, eletriptan, or ubrelvy) but it’s so hard to say confidently if it does anything. Whether or not my migraine gets worse,
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10 available comparisons
Dosage Forms
Tablet
Route
Oral