Question 1

What is ENSARTINIB used for?

Accepted Answer

ENSARTINIB (brand name ENSACOVE) is a Other indicated for 2.1 ).

Question 2

How does ENSARTINIB work?

Accepted Answer

ENSARTINIB works through the following mechanism: 12.1 Mechanism of Action Ensartinib is a kinase inhibitor of anaplastic lymphoma kinase (ALK) and inhibits other kinases including MET and ROS1. In vitro, ensartinib inhibited phosphorylation of ALK and its downstream signaling proteins AKT, ERK, and S6, thereby blocking ALK-mediated signaling pathways and inhibiting proliferation in cell lines harboring ALK fusions and mutations. In vivo, ensartinib showed anti-tumor activity in a mouse xenograft model of human NSCLC harboring an ALK fusion..

Question 3

What are the most common side effects of ENSARTINIB?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for ENSARTINIB. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is ENSARTINIB the same as ENSACOVE?

Accepted Answer

ENSACOVE is a brand name for ENSARTINIB. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

ENSARTINIB

Mechanism of Action

Indications

FDA Warnings

Known Side Effects

Community Discussions

Primary sources

Compare With

Formulations