How does ERGOTAMINE TARTRATE AND CAFFEINE work?

ERGOTAMINE TARTRATE AND CAFFEINE works through the following mechanism: CNS Stimulant agent.

What are the most common side effects of ERGOTAMINE TARTRATE AND CAFFEINE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for ERGOTAMINE TARTRATE AND CAFFEINE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is ERGOTAMINE TARTRATE AND CAFFEINE the same as its brand-name version?

ERGOTAMINE TARTRATE AND CAFFEINE is the generic name. The active ingredient is the same across any brand-name or generic versions approved by the FDA.

ERGOTAMINE TARTRATE AND CAFFEINE

Q: What is ERGOTAMINE TARTRATE AND CAFFEINE used for?

ERGOTAMINE TARTRATE AND CAFFEINE is a CNS Stimulant indicated for INDICATIONS AND USAGE Ergotamine Tartrate and Caffeine Indicated as therapy to abort or prevent vascular headache, e.g., migraine.

CNS Stimulant

Rectal

Mechanism of Action

CNS Stimulant agent

Indications

INDICATIONS AND USAGE Ergotamine Tartrate and Caffeine Indicated as therapy to abort or prevent vascular headache

e.g.

migraine

migraine variants or so-called “histaminic cephalalgia”.

Contraindications

• CONTRAINDICATIONS Coadministration of ergotamine with potent CYP 3A4 inhibitors (ritonavir
• nelfinavir
• indinavir
• erythromycin
• clarithromycin

FDA Warnings

WARNING Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of ergotamine tartrate and caffeine with potent CYP 3A4 inhibitors including protease inhibitors and macrolide antibiotics
Because CYP 3A4 inhibition elevates the serum levels of ergotamine tartrate and caffeine, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased
Hence, concomitant use of these medications is contraindicated
(See also CONTRAINDICATIONS and WARNINGS section)

Known Side Effects

6 documented side effects by frequency

Drug Not Working

>10%

Headache

1-10%

Nausea

1-10%

Chest Pain

0.1-1%

Shortness of Breath

0.1-1%

Fever

0.1-1%

Community Discussions

3 Reddit threads analysed for ERGOTAMINE TARTRATE AND CAFFEINE

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

8 upvotes

Most discussed side effects in community

Headache (3)

Patient Experiences (r/pharmacy, r/AskDocs & more)

After 30 years of migraines here are the drugs and treatments I've tried and maybe my experiences may help some of you..…

I get severe non visual migraines lasting from 6 hours to 2 days with vomiting and diarrhoea, started at the age of 9. At worst 3 or 4 attacks a month. (m) Cafergot - ergotamine tartrate and caffeine. Worked very well but dr pulled me off it as the side effects can cause heart and liver problems. Th

r/migraine201312y ago

Headache

Can't map to a trigger!

I've been having migraine attacks since 14M years currently 26. I have migraines with or without Aura. Aura migraines happens only 2-3 times a year. As a confused kid, I went to an eye specialist then thinking it's related to some eye issue. I was presribed Vit A meds and it significantly reduced th

r/migraine371y ago

Headache

Frequent Headaches of Different Types

Hi! I'm sorry I think posts on headaches are really common and I don't think this is a super serious or life threatening situation, I'm just seeking some opinions or similar experiences! I've searched this sub for headache posts but none really seem to fit my situation so I thought I'd try my luck w

r/AskDocs246y ago

Headache

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → ERGOTAMINE TARTRATE AND CAFFEINE openFDA label JSON → ERGOTAMINE TARTRATE AND CAFFEINE FAERS adverse-event reports → ERGOTAMINE TARTRATE AND CAFFEINE ClinicalTrials.gov → completed Phase 2+ trials of ERGOTAMINE TARTRATE AND CAFFEINE

Compare With

14 available comparisons

Formulations

Dosage Forms

Tablet

Route

Rectal