Brand names: Fluticasone Propionate and Salmeterol
12.1 Mechanism of Action This product contains both fluticasone propionate and salmeterol. The mechanisms of action described below for the individual components apply to this combination product. These drugs represent 2 different classes of medications (a synthetic corticosteroid and a LABA) that have different effects on clinical, physiologic, and inflammatory indices. Fluticasone Propionate : Fluticasone propionate is a synthetic trifluorinated corticosteroid with anti-inflammatory activity. Fluticasone propionate has been shown in vitro to exhibit a binding affinity for the human glucocorticoid receptor that is 18 times that of dexamethasone, almost twice that of beclomethasone-17-monopropionate (BMP), the active metabolite of beclomethasone dipropionate, and over 3 times that of budesonide. Data from the McKenzie vasoconstrictor assay in humans are consistent with these results. The clinical significance of these findings is unknown. Inflammation is an important component in the p
9 documented side effects by frequency
5 Reddit threads analysed for FLUTICASONE PROPIONATE AND SALMETEROL
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
25 upvotes
Most discussed side effects in community
Threads directly comparing FLUTICASONE PROPIONATE AND SALMETEROL to other medications
Hey guys, So I'd known for a long time that using a spacer with MDIs help improve medication delivery to the lungs, but today I learned how dramatic the effects are. Thought this would be worth sharing with y'all since these details might not be common knowledge. Maybe it'll come in handy sometime.
3x Essie Check Your Baggage 2x Nails Inc Make It Mystical 1x Essie Gel Setter 250/50 Wixela 🤣
Hi Reddit, I am writing this post in hoping that someone here might have insights or suggestions. I am 25 years old, fit (I play football semi-professional), and have been dealing with asthma symptoms for the past three years. Despite seeing multiple doctors and trying a wide range of treatments, my
I've had asthma issues since my teen years and am currently using Wixela (fluticasone propionate and salmeterol inhaler), montelukast, and albuterol. In the last six months my family acquired a rabbit. It's become rather clear to me that my breathing is notably worse since the rabbit took up resid
Looking for pharmacy recommendations and/or experiences purchasing asthma medication (in my case fluticasone propionate and salmeterol or Wixela/Advair) from Canada to be shipped to the US. ​ From my internet research it seems that this isn't entirely illegal for personal importation and
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Every figure on this page links back to its primary source. See data sources for full provenance.
15 available comparisons
Dosage Forms
Tablet
Route
Respiratory (inhalation)