Question 1

What is FOSTAMATINIB used for?

Accepted Answer

FOSTAMATINIB (brand name TAVALISSE) is a Other indicated for See full prescribing information.

Question 2

How does FOSTAMATINIB work?

Accepted Answer

FOSTAMATINIB works through the following mechanism: 12.1 Mechanism of Action Fostamatinib is a tyrosine kinase inhibitor with demonstrated activity against spleen tyrosine kinase (SYK). The major metabolite of fostamatinib, R406, inhibits signal transduction of Fc-activating receptors and B-cell receptor. The fostamatinib metabolite R406 reduces antibody-mediated destruction of platelets..

Question 3

What are the most common side effects of FOSTAMATINIB?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for FOSTAMATINIB. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is FOSTAMATINIB the same as TAVALISSE?

Accepted Answer

TAVALISSE is a brand name for FOSTAMATINIB. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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