What is GLYCOPYRRONIUM used for?

GLYCOPYRRONIUM (brand name Qbrexza) is a Other indicated for See full prescribing information.

What are the most common side effects of GLYCOPYRRONIUM?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for GLYCOPYRRONIUM. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is GLYCOPYRRONIUM the same as Qbrexza?

Qbrexza is a brand name for GLYCOPYRRONIUM. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

GLYCOPYRRONIUM

Q: How does GLYCOPYRRONIUM work?

GLYCOPYRRONIUM works through the following mechanism: 12.1 Mechanism of Action Glycopyrronium is a competitive inhibitor of acetylcholine receptors that are located on certain peripheral tissues, including sweat glands. In hyperhidrosis, glycopyrronium inhibits the action of acetylcholine on sweat glands, reducing sweating..

Other

Brand names: Qbrexza

Topical

Mechanism of Action

12.1 Mechanism of Action Glycopyrronium is a competitive inhibitor of acetylcholine receptors that are located on certain peripheral tissues, including sweat glands. In hyperhidrosis, glycopyrronium inhibits the action of acetylcholine on sweat glands, reducing sweating.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS Qbrexza is contraindicated in patients with medical conditions that can be exacerbated by the anticholinergic effect of Qbrexza (e.g.
• glaucoma
• paralytic ileus
• unstable cardiovascular status in acute hemorrhage
• severe ulcerative colitis

FDA Warnings

5 WARNINGS AND PRECAUTIONS New or worsening urinary retention: Use with caution in patients with a history of documented urinary retention ( 5
4 Risk of Accidental Exposure Cases of accidental exposure resulting in mydriasis, anisocoria, and blurred vision have been reported in postmarketing surveillance of Qbrexza
The risk of accidental exposure was increased in these cases by not adhering to recommendations for the appropriate use of Qbrexza

Known Side Effects

8 documented side effects by frequency

Dry Mouth

>10%

Blurred Vision

>10%

Drug Not Working

1-10%

Headache

0.1-1%

Constipation

0.1-1%

Shortness of Breath

0.1-1%

Excessive Sweating

0.1-1%

Nausea

0.1-1%

Community Discussions

No community discussions found for GLYCOPYRRONIUM yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → GLYCOPYRRONIUM openFDA label JSON → GLYCOPYRRONIUM FAERS adverse-event reports → GLYCOPYRRONIUM ClinicalTrials.gov → completed Phase 2+ trials of GLYCOPYRRONIUM

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Formulations

Dosage Forms

Tablet

Route

Topical