How does IMIPRAMINE HYDROCHLORIDE work?

IMIPRAMINE HYDROCHLORIDE works through the following mechanism: Other agent.

What are the most common side effects of IMIPRAMINE HYDROCHLORIDE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for IMIPRAMINE HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is IMIPRAMINE HYDROCHLORIDE the same as Imipramine Hydrochloride?

Imipramine Hydrochloride is a brand name for IMIPRAMINE HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

IMIPRAMINE HYDROCHLORIDE

Q: What is IMIPRAMINE HYDROCHLORIDE used for?

IMIPRAMINE HYDROCHLORIDE (brand name Imipramine Hydrochloride) is a Tricyclic Antidepressant indicated for after possible organic causes have been excluded by appropriate tests. In patients having daytime symptoms of frequency and urgency, examination should include voiding cystourethrography and cystoscopy, as necessary. The effectiveness of treatment may decrease with continued drug administration..

Tricyclic Antidepressant

Brand names: Imipramine Hydrochloride

Oral

Mechanism of Action

Other agent

Indications

after possible organic causes have been excluded by appropriate tests. In patients having daytime symptoms of frequency and urgency

examination should include voiding cystourethrography and cystoscopy

as necessary. The effectiveness of treatment may decrease with continued drug administration.

Contraindications

• or even fatal. When it is desired to substitute imipramine hydrochloride in patients receiving a monoamine oxidase inhibitor
• as long an interval should elapse as the clinical situation will allow

FDA Warnings

Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders
Anyone considering the use of imipramine hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need
Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide

Known Side Effects

10 documented side effects by frequency

Dizziness

1-10%

Drug Not Working

1-10%

Fatigue

1-10%

High Blood Pressure

1-10%

Depression

1-10%

Anxiety

1-10%

Nausea

1-10%

Headache

1-10%

Shortness of Breath

1-10%

Weakness

1-10%

Community Discussions

1 Reddit threads analysed for IMIPRAMINE HYDROCHLORIDE

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

388 upvotes

Most discussed side effects in community

Weight Gain (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

Ther dangers of adderall and productivity…

I’ve talked about my experience with Adderall, vyvanse, and imipramine (9/10, -10000/10, 7/10) in the past. Due to some health issues I moved to Nortriptyline. Massive weight gain. Ended up having my gallbladder removed in April and doc decided to take me off Nortriptyline as the symptoms I had pri

r/adhdwomen3883011mo ago

Weight Gain

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → IMIPRAMINE HYDROCHLORIDE openFDA label JSON → IMIPRAMINE HYDROCHLORIDE FAERS adverse-event reports → IMIPRAMINE HYDROCHLORIDE ClinicalTrials.gov → completed Phase 2+ trials of IMIPRAMINE HYDROCHLORIDE

Compare With

12 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral