Question 1

What is IMLUNESTRANT used for?

Accepted Answer

IMLUNESTRANT (brand name Inluriyo) is a Other indicated for 1 INDICATIONS AND USAGE INLURIYO is indicated for the treatment of adults with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, HER2-negative.

Question 2

How does IMLUNESTRANT work?

Accepted Answer

IMLUNESTRANT works through the following mechanism: 12.1 Mechanism of Action Imlunestrant is an estrogen receptor (ER) antagonist that binds to ERα. In vitro, imlunestrant induced degradation of ERα, leading to inhibition of ER-dependent gene transcription and cellular proliferation in ER+ breast cancer cells. Imlunestrant demonstrated in vitro and in vivo anti-tumor activity in ER+ breast cancer xenograft models, including models with ESR1 mutations..

Question 3

What are the most common side effects of IMLUNESTRANT?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for IMLUNESTRANT. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is IMLUNESTRANT the same as Inluriyo?

Accepted Answer

Inluriyo is a brand name for IMLUNESTRANT. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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