What is LETERMOVIR used for?

LETERMOVIR (brand name PREVYMIS) is a Other indicated for See full prescribing information.

How does LETERMOVIR work?

LETERMOVIR works through the following mechanism: 12.1 Mechanism of Action PREVYMIS is an antiviral drug against CMV [see Microbiology (12.4) ] ..

What are the most common side effects of LETERMOVIR?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for LETERMOVIR. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is LETERMOVIR the same as PREVYMIS?

PREVYMIS is a brand name for LETERMOVIR. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

LETERMOVIR

Other

Brand names: PREVYMIS

Oral, Intravenous

Mechanism of Action

12.1 Mechanism of Action PREVYMIS is an antiviral drug against CMV [see Microbiology (12.4) ] .

Indications

See full prescribing information

Contraindications

• which may lead to QT prolongation and torsades de pointes [see Warnings and Precautions (5.1) and Drug Interactions (7.2
• which may lead to ergotism [see Warnings and Precautions (5.1) and Drug Interactions (7.2
• which may lead to myopathy or rhabdomyolysis [see Warnings and Precautions (5.1) and Drug Interactions (7.2
• 7.3) ] . PREVYMIS is contraindicated with: Pimozide. ( 4 ) Ergot Alkaloids. ( 4 ) Pitavastatin and simvastatin when co-administered with cyclosporine. ( 4 )

FDA Warnings

5 WARNINGS AND PRECAUTIONS Risk of Adverse Reactions or Reduced Therapeutic Effect Due to Drug Interactions: The concomitant use of PREVYMIS with certain drugs may result in potentially significant drug interactions, some of which may lead to adverse reactions (PREVYMIS or concomitant drugs) or reduced therapeutic effect of PREVYMIS or the concomitant drug
3 ) Risks Associated with Hydroxypropyl Betadex Excipient in Intravenous Formulation: Intravenous formulation of PREVYMIS contains the excipient hydroxypropyl betadex
1 Risk of Adverse Reactions or Reduced Therapeutic Effect Due to Drug Interactions The concomitant use of PREVYMIS and certain drugs may result in potentially significant drug interactions, some of which may lead to adverse reactions (PREVYMIS or concomitant drugs) or reduced therapeutic effect of PREVYMIS or the concomitant drug [see Contraindications (4) and Drug Interactions (7
2 Risks Associated with Hydroxypropyl Betadex Excipient in Intravenous Formulation Intravenous formulation of PREVYMIS contains the excipient hydroxypropyl betadex

Known Side Effects

2 documented side effects by frequency

Drug Not Working

>10%

Diarrhea

0.1-1%

Community Discussions

No community discussions found for LETERMOVIR yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → LETERMOVIR openFDA label JSON → LETERMOVIR FAERS adverse-event reports → LETERMOVIR ClinicalTrials.gov → completed Phase 2+ trials of LETERMOVIR

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Formulations

Dosage Forms

Tablet

Route

Oral, Intravenous