What is LEUCOVORIN CALCIUM used for?

LEUCOVORIN CALCIUM (brand name LEUCOVORIN CALCIUM) is a Electrolyte / Mineral indicated for See full prescribing information.

How does LEUCOVORIN CALCIUM work?

LEUCOVORIN CALCIUM works through the following mechanism: Other agent.

What are the most common side effects of LEUCOVORIN CALCIUM?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for LEUCOVORIN CALCIUM. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is LEUCOVORIN CALCIUM the same as LEUCOVORIN CALCIUM?

LEUCOVORIN CALCIUM is a brand name for LEUCOVORIN CALCIUM. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

LEUCOVORIN CALCIUM

Electrolyte / Mineral

Brand names: LEUCOVORIN CALCIUM

Pregnancy: Category CIntramuscular, Intravenous

Mechanism of Action

Other agent

Indications

See full prescribing information

FDA Warnings

WARNINGS In the treatment of accidental overdosages of folic acid antagonists, intravenous leucovorin should be administered as promptly as possible
LEUCOVORIN MAY BE HARMFUL OR FATAL IF GIVEN INTRATHECALLY
Patients with diarrhea must be monitored with particular care until the diarrhea has resolved, as rapid clinical deterioration leading to death can occur
In an additional study utilizing higher weekly doses of 5-fluorouracil and leucovorin, elderly and/or debilitated patients were found to be at greater risk for severe gastrointestinal toxicity

Known Side Effects

9 documented side effects by frequency

Diarrhea

>10%

Nausea

>10%

Vomiting

1-10%

Fever

1-10%

Fatigue

1-10%

Drug Not Working

1-10%

Shortness of Breath

1-10%

Weakness

0.1-1%

Abdominal Pain

0.1-1%

Community Discussions

No community discussions found for LEUCOVORIN CALCIUM yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → LEUCOVORIN CALCIUM openFDA label JSON → LEUCOVORIN CALCIUM FAERS adverse-event reports → LEUCOVORIN CALCIUM ClinicalTrials.gov → completed Phase 2+ trials of LEUCOVORIN CALCIUM

Compare With

0 available comparisons

No comparisons yet.

Formulations

Dosage Forms

Tablet

Route

Intramuscular, Intravenous