Question 1

What is LOMITAPIDE MESYLATE used for?

Accepted Answer

LOMITAPIDE MESYLATE (brand name Juxtapid) is a Other indicated for to reduce LDL-C in adult and pediatric patients aged 2 years and older with HoFH. ( 1 )..

Question 2

How does LOMITAPIDE MESYLATE work?

Accepted Answer

LOMITAPIDE MESYLATE works through the following mechanism: 12.1 Mechanism of Action JUXTAPID directly binds and inhibits microsomal triglyceride transfer protein (MTP), which resides in the lumen of the endoplasmic reticulum, thereby preventing the assembly of apo B-containing lipoproteins in enterocytes and hepatocytes. This inhibits the synthesis of chylomicrons and VLDL. The inhibition of the synthesis of VLDL leads to reduced levels of plasma LDL-C..

Question 3

What are the most common side effects of LOMITAPIDE MESYLATE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for LOMITAPIDE MESYLATE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is LOMITAPIDE MESYLATE the same as Juxtapid?

Accepted Answer

Juxtapid is a brand name for LOMITAPIDE MESYLATE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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