What is LOPERAMIDE HYDROCHLORIDE used for?

LOPERAMIDE HYDROCHLORIDE (brand name Loperamide Hydrochloride) is a Antidiarrheal indicated for See full prescribing information.

How does LOPERAMIDE HYDROCHLORIDE work?

LOPERAMIDE HYDROCHLORIDE works through the following mechanism: Other agent.

What are the most common side effects of LOPERAMIDE HYDROCHLORIDE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for LOPERAMIDE HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is LOPERAMIDE HYDROCHLORIDE the same as Loperamide Hydrochloride?

Loperamide Hydrochloride is a brand name for LOPERAMIDE HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

LOPERAMIDE HYDROCHLORIDE

Antidiarrheal

Brand names: Loperamide Hydrochloride

Oral

Mechanism of Action

Other agent

Indications

See full prescribing information

Contraindications

• which is characterized by blood in stools and high fever. patients with acute ulcerative colitis. patients with bacterial enterocolitis caused by invasive organisms including Salmonella
• Shigella
• and Campylobacter . patients with pseudomembranous colitis (e.g.
• Clostridium difficle ) associated with the use of broad-spectrum antibiotics.

FDA Warnings

WARNING: TORSADES DE POINTES AND SUDDEN DEATH Cases of Torsades de Pointes, cardiac arrest, and death have been reported with the use of a higher than recommended dosage of loperamide hydrochloride capsules (see WARNINGS and OVERDOSAGE )
Loperamide hydrochloride capsules are contraindicated in pediatric patients less than 2 years of age (see CONTRAINDICATIONS )
Avoid loperamide hydrochloride capsules dosages higher than recommended in adults and pediatric patients 2 years of age and older due to the risk of serious cardiac adverse reactions (see DOSAGE AND ADMINISTRATION )

Known Side Effects

13 documented side effects by frequency

Diarrhea

>10%

Drug Not Working

>10%

Nausea

1-10%

Fatigue

1-10%

Vomiting

1-10%

Constipation

1-10%

Weight Loss

0.1-1%

Shortness of Breath

0.1-1%

Headache

0.1-1%

Abdominal Pain

0.1-1%

Weakness

0.1-1%

Decreased Appetite

0.1-1%

Dizziness

0.1-1%

Community Discussions

1 Reddit threads analysed for LOPERAMIDE HYDROCHLORIDE

Overall Sentiment

Mixed

Comparison Threads

Avg Post Score

1 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

Urgent Article Request

Anyone out there with access to the Annals of Pharmacotherapy, I would be extremely grateful if you could pull up and PM me "Appendicitis associated with loperamide hydrochloride abuse," Katz JP, Sturmann KM. 1993 Mar;27(3):369-70. You can now resume looking at pictures of cats.

r/pharmacy1613y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → LOPERAMIDE HYDROCHLORIDE openFDA label JSON → LOPERAMIDE HYDROCHLORIDE FAERS adverse-event reports → LOPERAMIDE HYDROCHLORIDE ClinicalTrials.gov → completed Phase 2+ trials of LOPERAMIDE HYDROCHLORIDE

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Formulations

Dosage Forms

Tablet

Route

Oral