How does METRONIDAZOLE ORAL work?

METRONIDAZOLE ORAL works through the following mechanism: 12.1 Mechanism of Action Metronidazole is a nitroimidazole antimicrobial drug [ see Microbiology (12.4) ] ..

What are the most common side effects of METRONIDAZOLE ORAL?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for METRONIDAZOLE ORAL. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is METRONIDAZOLE ORAL the same as LIKMEZ?

LIKMEZ is a brand name for METRONIDAZOLE ORAL. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

METRONIDAZOLE ORAL

Q: What is METRONIDAZOLE ORAL used for?

METRONIDAZOLE ORAL (brand name LIKMEZ) is a Antifungal indicated for cervicitis, or cervical erosion. Because trichomoniasis is a sexually transmitted disease with potentially serious sequelae, including peritonitis.

Antifungal

Brand names: LIKMEZ

Oral

Mechanism of Action

12.1 Mechanism of Action Metronidazole is a nitroimidazole antimicrobial drug [ see Microbiology (12.4) ] .

Indications

cervicitis

or cervical erosion. Because trichomoniasis is a sexually transmitted disease with potentially serious sequelae

including peritonitis

intra-abdominal abscess

and liver abscess

caused by Bacteroides species including the B. fragilis group ( B. fragilis

Contraindications

• 4 CONTRAINDICATIONS Prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives ( 4.1 ) Patients who have used disulfiram within the last two weeks. ( 4.2
• 7.1 ) Patients who consume alcohol or products containing propylene glycol during and for at least three days after LIKMEZ therapy. ( 4.3
• 7.2 ) Patients with Cockayne syndrome ( 4.4
• including abdominal cramps
• nausea

FDA Warnings

5 WARNINGS AND PRECAUTIONS Central and Peripheral Nervous System Effects: Encephalopathy, convulsive seizures, aseptic meningitis and peripheral neuropathy have been reported with metronidazole
Promptly evaluate the benefit/risk of continuation of LIKMEZ if abnormal neurological signs develop
The appearance of abnormal neurological signs and symptoms demands the prompt evaluation of the benefit/risk ratio of the continuation of therapy
5 Drug-Resistant Bacteria Prescribing LIKMEZ in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria

Known Side Effects

12 documented side effects by frequency

Drug Not Working

>10%

Nausea

1-10%

Diarrhea

1-10%

Vomiting

1-10%

Fever

1-10%

Abdominal Pain

1-10%

Headache

1-10%

Fatigue

1-10%

Shortness of Breath

0.1-1%

Dizziness

0.1-1%

Condition Worsened

0.1-1%

General Unwellness

0.1-1%

Community Discussions

No community discussions found for METRONIDAZOLE ORAL yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → METRONIDAZOLE ORAL openFDA label JSON → METRONIDAZOLE ORAL FAERS adverse-event reports → METRONIDAZOLE ORAL ClinicalTrials.gov → completed Phase 2+ trials of METRONIDAZOLE ORAL

Compare With

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Formulations

Dosage Forms

Tablet

Route

Oral