Question 1

What is MEXILETINE HYDROCHLORIDE used for?

Accepted Answer

MEXILETINE HYDROCHLORIDE (brand name Mexiletine Hydrochloride) is a Electrolyte / Mineral indicated for INDICATIONS AND USAGE Mexiletine Hydrochloride Capsules USP are indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that.

Question 2

How does MEXILETINE HYDROCHLORIDE work?

Accepted Answer

MEXILETINE HYDROCHLORIDE works through the following mechanism: Mechanism of Action Mexiletine hydrochloride is a local anesthetic, antiarrhythmic agent, structurally similar to lidocaine, but orally active. In animal studies, mexiletine has been shown to be effective in the suppression of induced ventricular arrhythmias, including those induced by glycoside toxicity and coronary artery ligation. Mexiletine, like lidocaine, inhibits the inward sodium current, thus reducing the rate of rise of the action potential, Phase 0. Mexiletine decreased the effective refractory period (ERP) in Purkinje fibers. The decrease in ERP was of lesser magnitude than the decrease in action potential duration (APD), with a resulting increase in the ERP/APD ratio..

Question 3

What are the most common side effects of MEXILETINE HYDROCHLORIDE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for MEXILETINE HYDROCHLORIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is MEXILETINE HYDROCHLORIDE the same as Mexiletine Hydrochloride?

Accepted Answer

Mexiletine Hydrochloride is a brand name for MEXILETINE HYDROCHLORIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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