Question 1

What is MIFEPRISTONE used for?

Accepted Answer

MIFEPRISTONE (brand name Korlym) is a Other indicated for See full prescribing information.

Question 2

How does MIFEPRISTONE work?

Accepted Answer

MIFEPRISTONE works through the following mechanism: 12.1 Mechanism of Action Mifepristone is a selective antagonist of the progesterone receptor at low doses and blocks the glucocorticoid receptor (GR-II) at higher doses. Mifepristone has high affinity for the GR-II receptor but little affinity for the GR-I (MR, mineralocorticoid) receptor. In addition, mifepristone appears to have little or no affinity for estrogen, muscarinic, histaminic, or monoamine receptors..

Question 3

What are the most common side effects of MIFEPRISTONE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for MIFEPRISTONE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is MIFEPRISTONE the same as Korlym?

Accepted Answer

Korlym is a brand name for MIFEPRISTONE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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