Brand names: Naproxen Oral Suspension
12.1 Mechanism of Action Naproxen has analgesic, anti-inflammatory, and antipyretic properties. The mechanism of action of naproxen, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Naproxen is a potent inhibitor of prostaglandin synthesis in vitro. Naproxen concentrations reached during therapy have produced in vivo effects. Prostaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain in animal models. Prostaglandins are mediators of inflammation. Because naproxen is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.
Contraindications
12 documented side effects by frequency
No community discussions found for NAPROXEN ORAL yet.
Every figure on this page links back to its primary source. See data sources for full provenance.
0 available comparisons
No comparisons yet.
Dosage Forms
Tablet
Route
Oral