Question 1

What is NATEGLINIDE used for?

Accepted Answer

NATEGLINIDE (brand name Nateglinide) is a Other indicated for See full prescribing information.

Question 2

How does NATEGLINIDE work?

Accepted Answer

NATEGLINIDE works through the following mechanism: 12.1 Mechanism of Action Nateglinide lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets. Nateglinide interacts with the ATP-sensitive potassium (K + ATP ) channel on pancreatic beta-cells. The subsequent depolarization of the beta cell opens the calcium channel, producing calcium influx and insulin secretion. The extent of insulin release is glucose dependent and diminishes at low glucose levels. Nateglinide is highly tissue selective with low affinity for heart and skeletal muscle..

Question 3

What are the most common side effects of NATEGLINIDE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for NATEGLINIDE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is NATEGLINIDE the same as Nateglinide?

Accepted Answer

Nateglinide is a brand name for NATEGLINIDE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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