How does NORTRIPTYLINE HCL work?

NORTRIPTYLINE HCL works through the following mechanism: Other agent.

What are the most common side effects of NORTRIPTYLINE HCL?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for NORTRIPTYLINE HCL. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is NORTRIPTYLINE HCL the same as Nortriptyline HCL?

Nortriptyline HCL is a brand name for NORTRIPTYLINE HCL. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

NORTRIPTYLINE HCL

Q: What is NORTRIPTYLINE HCL used for?

NORTRIPTYLINE HCL (brand name Nortriptyline HCL) is a Tricyclic Antidepressant indicated for Nortriptyline hydrochloride, USP is indicated for the relief of symptoms of depression. Endogenous depressions are more likely to be alleviated than are other depressive states..

Tricyclic Antidepressant

Brand names: Nortriptyline HCL

Oral

Mechanism of Action

Other agent

Indications

Nortriptyline hydrochloride

USP is indicated for the relief of symptoms of depression. Endogenous depressions are more likely to be alleviated than are other depressive states.

FDA Warnings

SUICIDALITY AND ANTIDEPRESSANT DRUGS Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders
Anyone considering the use of nortriptyline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need
Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide

Known Side Effects

8 documented side effects by frequency

Drug Not Working

>10%

Headache

1-10%

Fatigue

1-10%

Nausea

1-10%

Excessive Sweating

1-10%

High Blood Pressure

1-10%

Constipation

1-10%

Back Pain

0.1-1%

Community Discussions

No community discussions found for NORTRIPTYLINE HCL yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → NORTRIPTYLINE HCL openFDA label JSON → NORTRIPTYLINE HCL FAERS adverse-event reports → NORTRIPTYLINE HCL ClinicalTrials.gov → completed Phase 2+ trials of NORTRIPTYLINE HCL

Compare With

12 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral