Brand names: Pentetate zinc trisodium
12.1 Mechanism of Action Zn-DTPA forms stable chelates with metal ions by exchanging zinc for a metal of greater binding capacity. The radioactive chelates are then excreted by glomerular filtration into the urine. In animal studies, Zn-DTPA forms less stable chelates with uranium and neptunium in vivo resulting in deposition of these elements in tissues including the bone. Zn-DTPA treatments are not expected to be effective for uranium and neptunium. Radioactive iodine is not bound by DTPA.
Contraindications
8 documented side effects by frequency
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Dosage Forms
Tablet
Route
Intravenous, Respiratory (inhalation)