What are the most common side effects of PINDOLOL?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for PINDOLOL. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is PINDOLOL the same as Pindolol?

Pindolol is a brand name for PINDOLOL. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

PINDOLOL

Q: What is PINDOLOL used for?

PINDOLOL (brand name Pindolol) is a Beta Blocker indicated for INDICATIONS AND USAGE Pindolol tablets are indicated in the management of hypertension. It may be used alone or concomitantly with other antihypertensive agents, particularly with a thiazide-type diuretic..

Q: How does PINDOLOL work?

PINDOLOL works through the following mechanism: PHARMACODYNAMICS In standard pharmacologic tests in man and animals, pindolol attenuates increases in heart rate, systolic blood pressure, and cardiac output resulting from exercise and isoproterenol administration, thus confirming its beta-blocking properties. The ISA or partial agonist activity of pindolol is mediated directly at the adrenergic receptor sites and may be blocked by other beta-blockers. In catecholamine depleted animal experiments, ISA is manifested as an increase in the inotrop.

Beta Blocker

Brand names: Pindolol

Oral

Mechanism of Action

PHARMACODYNAMICS In standard pharmacologic tests in man and animals, pindolol attenuates increases in heart rate, systolic blood pressure, and cardiac output resulting from exercise and isoproterenol administration, thus confirming its beta-blocking properties. The ISA or partial agonist activity of pindolol is mediated directly at the adrenergic receptor sites and may be blocked by other beta-blockers. In catecholamine depleted animal experiments, ISA is manifested as an increase in the inotrop

Indications

INDICATIONS AND USAGE Pindolol tablets are indicated in the management of hypertension. It may be used alone or concomitantly with other antihypertensive agents

particularly with a thiazide-type diuretic.

Contraindications

• CONTRAINDICATIONS Pindolol tablets are contraindicated in: 1) bronchial asthma
• 2) overt cardiac failure
• 3) cardiogenic shock
• 4) second and third degree heart block
• 5) severe bradycardia. (See WARNINGS. )

FDA Warnings

WARNINGS Cardiac Failure Sympathetic stimulation may be a vital component supporting circulatory function in patients with congestive heart failure, and its inhibition by beta-blockade may precipitate more severe failure
Concomitant use can increase risk of bradycardia
Major Surgery Because beta-blockade impairs the ability of the heart to respond to reflex stimuli and may increase the risks of general anesthesia and surgical procedures, resulting in protracted hypotension or low cardiac output, it has generally been suggested that such therapy should be gradually withdrawn several days prior to surgery

Known Side Effects

10 documented side effects by frequency

Drug Not Working

1-10%

Fatigue

1-10%

Nausea

1-10%

UTI

1-10%

Dizziness

1-10%

Shortness of Breath

1-10%

Falls

1-10%

Diarrhea

1-10%

Headache

0.1-1%

Muscle Pain

0.1-1%

Community Discussions

No community discussions found for PINDOLOL yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → PINDOLOL openFDA label JSON → PINDOLOL FAERS adverse-event reports → PINDOLOL ClinicalTrials.gov → completed Phase 2+ trials of PINDOLOL

Compare With

13 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral