How does PIPERACILLIN AND TAZOBACTAM work?

PIPERACILLIN AND TAZOBACTAM works through the following mechanism: 12.1 Mechanism of Action Piperacillin and tazobactam is an antibacterial drug [see Microbiology ( 12.4 )] ..

What are the most common side effects of PIPERACILLIN AND TAZOBACTAM?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for PIPERACILLIN AND TAZOBACTAM. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is PIPERACILLIN AND TAZOBACTAM the same as Piperacillin and Tazobactam?

Piperacillin and Tazobactam is a brand name for PIPERACILLIN AND TAZOBACTAM. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

PIPERACILLIN AND TAZOBACTAM

Q: What is PIPERACILLIN AND TAZOBACTAM used for?

PIPERACILLIN AND TAZOBACTAM (brand name Piperacillin and Tazobactam) is a Penicillin Antibiotic indicated for 1 INDICATIONS AND USAGE Piperacillin and tazobactam for injection, for intravenous use is a combination of piperacillin, a penicillin-class antibacterial and tazobactam.

Penicillin Antibiotic

Brand names: Piperacillin and Tazobactam

Intravenous

Mechanism of Action

12.1 Mechanism of Action Piperacillin and tazobactam is an antibacterial drug [see Microbiology ( 12.4 )] .

Indications

1 INDICATIONS AND USAGE Piperacillin and tazobactam for injection

for intravenous use is a combination of piperacillin

a penicillin-class antibacterial and tazobactam

USP and other antibacterial drugs

Piperacillin and Tazobactam for Injection

B. ovatus

Contraindications

• 4 CONTRAINDICATIONS Piperacillin and tazobactam for injection is contraindicated in patients with a history of allergic reactions to any of the penicillins
• cephalosporins
• or beta-lactamase inhibitors. Patients with a history of allergic reactions to any of the penicillins
• cephalosporins
• or beta-lactamase inhibitors. ( 4 )

FDA Warnings

5 WARNINGS AND PRECAUTIONS • Serious hypersensitivity reactions (anaphylactic/anaphylactoid) have been reported in patients receiving piperacillin and tazobactam
Patients receiving higher doses, especially in the presence of renal impairment may be at greater risk
6 ) • Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients
1 Hypersensitivity Adverse Reactions Serious and occasionally fatal hypersensitivity (anaphylactic/anaphylactoid) reactions (including shock) have been reported in patients receiving therapy with piperacillin and tazobactam for injection

Known Side Effects

8 documented side effects by frequency

Drug Not Working

>10%

Fever

1-10%

Diarrhea

1-10%

Condition Worsened

1-10%

Shortness of Breath

0.1-1%

Rash

0.1-1%

Low Blood Pressure

0.1-1%

Nausea

0.1-1%

Community Discussions

No community discussions found for PIPERACILLIN AND TAZOBACTAM yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → PIPERACILLIN AND TAZOBACTAM openFDA label JSON → PIPERACILLIN AND TAZOBACTAM FAERS adverse-event reports → PIPERACILLIN AND TAZOBACTAM ClinicalTrials.gov → completed Phase 2+ trials of PIPERACILLIN AND TAZOBACTAM

Compare With

14 available comparisons

Formulations

Dosage Forms

Tablet

Route

Intravenous