What is PRILOCAINE HCL AND EPINEPHRINE used for?

PRILOCAINE HCL AND EPINEPHRINE is a Other indicated for See full prescribing information.

What are the most common side effects of PRILOCAINE HCL AND EPINEPHRINE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for PRILOCAINE HCL AND EPINEPHRINE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is PRILOCAINE HCL AND EPINEPHRINE the same as its brand-name version?

PRILOCAINE HCL AND EPINEPHRINE is the generic name. The active ingredient is the same across any brand-name or generic versions approved by the FDA.

PRILOCAINE HCL AND EPINEPHRINE

Q: How does PRILOCAINE HCL AND EPINEPHRINE work?

PRILOCAINE HCL AND EPINEPHRINE works through the following mechanism: Mechanism of Action Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action..

Other

Pregnancy: Category BSubmucosal

Mechanism of Action

Mechanism of Action Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.

Indications

See full prescribing information

FDA Warnings

WARNINGS DENTAL PRACTITIONERS WHO EMPLOY LOCAL ANESTHETIC AGENTS SHOULD BE WELL VERSED IN DIAGNOSIS AND MANAGEMENT OF EMERGENCIES THAT MAY ARISE FROM THEIR USE
Although all patients are at risk for methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants under 6 months of age, and concurrent exposure to oxidizing agents or their metabolites are more susceptible to developing clinical manifestations of the condition
Methemoglobin levels may continue to rise; therefore, immediate treatment is required to avert more serious central nervous system and cardiovascular adverse effects, including seizures, coma, arrhythmias, and death

Known Side Effects

9 documented side effects by frequency

Fatigue

>10%

Nausea

>10%

Diarrhea

1-10%

Vomiting

1-10%

Fever

1-10%

Headache

1-10%

Shortness of Breath

1-10%

Drug Not Working

1-10%

Dizziness

0.1-1%

Community Discussions

No community discussions found for PRILOCAINE HCL AND EPINEPHRINE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → PRILOCAINE HCL AND EPINEPHRINE openFDA label JSON → PRILOCAINE HCL AND EPINEPHRINE FAERS adverse-event reports → PRILOCAINE HCL AND EPINEPHRINE ClinicalTrials.gov → completed Phase 2+ trials of PRILOCAINE HCL AND EPINEPHRINE

Compare With

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Formulations

Dosage Forms

Tablet

Route

Submucosal