What are the most common side effects of QUETIAPINE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for QUETIAPINE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is QUETIAPINE the same as Quetiapine?

Quetiapine is a brand name for QUETIAPINE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

QUETIAPINE

Q: What is QUETIAPINE used for?

QUETIAPINE (brand name Quetiapine) is a Atypical Antipsychotic indicated for 1 INDICATIONS & USAGE Quetiapine is an atypical antipsychotic indicated for the treatment of: Schizophrenia ( 1.1 ) Bipolar I disorder manic episodes ( 1.2 ) Bipolar disorder, both as monotherapy and as an adjunct to lithium or divalproex. Efficacy was established in two 12-week monotherapy trials in adults, in one 3-week adjunctive trial in adults.

Q: How does QUETIAPINE work?

QUETIAPINE works through the following mechanism: 12.1 Mechanism of Action The mechanism of action of quetiapine in the listed indications is unclear. However, the efficacy of quetiapine in these indications could be mediated through a combination of dopamine type 2 (D 2 ) and serotonin type 2 (5HT 2 ) antagonism. The active metabolite, N-desalkyl quetiapine (norquetiapine), has similar activity at D 2 , but greater activity at 5HT2A receptors, than the parent drug (quetiapine)..

Atypical Antipsychotic

Brand names: Quetiapine, Seroquel

Oral

Mechanism of Action

12.1 Mechanism of Action The mechanism of action of quetiapine in the listed indications is unclear. However, the efficacy of quetiapine in these indications could be mediated through a combination of dopamine type 2 (D 2 ) and serotonin type 2 (5HT 2 ) antagonism. The active metabolite, N-desalkyl quetiapine (norquetiapine), has similar activity at D 2 , but greater activity at 5HT2A receptors, than the parent drug (quetiapine).

Indications

1 INDICATIONS & USAGE Quetiapine is an atypical antipsychotic indicated for the treatment of: Schizophrenia ( 1.1 ) Bipolar I disorder manic episodes ( 1.2 ) Bipolar disorder

both as monotherapy and as an adjunct to lithium or divalproex. Efficacy was established in two 12-week monotherapy trials in adults

in one 3-week adjunctive trial in adults

however

diagnosis can be challenging. For pediatric schizophrenia

symptom profiles can be variable

FDA Warnings

5 WARNINGS AND PRECAUTIONS · Cerebrovascular Adverse Reactions: Increased incidence of cerebrovascular adverse reactions (e
Monitor glucose regularly in patients with diabetes or at risk for diabetes · Dyslipidemia: Undesirable alterations have been observed in patients treated with atypical antipsychotics
1 Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death
Analysis of 17 placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1

Known Side Effects

9 documented side effects by frequency

Drug Not Working

1-10%

Insomnia

1-10%

Fatigue

1-10%

Weight Gain

1-10%

Drowsiness

1-10%

Nausea

1-10%

Depression

1-10%

Anxiety

1-10%

Dizziness

1-10%

Community Discussions

7 Reddit threads analysed for QUETIAPINE

Overall Sentiment

Mixed

Comparison Threads

Avg Post Score

96 upvotes

Most discussed side effects in community

Dizziness (1)

Fatigue (1)

Anxiety (1)

Drowsiness (1)

Stomach Pain (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

Healthcare in this country is a fucking scam

I turned 26 last year and got booted off my dad's insurance. I was still in school at the time and not working. I looked for coverage on the exchange and none of the plans would cover my antipsychotic (quetiapine/seroquel). I had to go on COBRA which meant I would be getting the same coverage that I

r/schizophrenia127486y ago

I've been starting to get a little manic the last few days so I channeled the energy into redoing my bathroom. OC

Yeah, it's been a bit weird. My psych and I are lowering my quetiapine in the hopes to get off it entirely because frankly, I'm suffocating under it. I knew I'd be signing up for some discomfort through this process; the balancing act is keeping it in the green and not tanking into someplace scary.

r/bipolar112102y ago

Just got the worst reaction ever from my Mum

I finally started medication (quetiapine + lamotrigine) today, after a really long mental battle, so I was feeling pretty proud and good after my psych appointment today. Then I came home, decided to tell my Mum (because she always complains I don’t tell her enough, I still live with her as I’m stil

r/bipolar110542y ago

You cannot win with Schizophrenia. Either the symptoms are debilitating or the side effects of the medication

I'm so tired. I've been suffering for months due to medication side effects. Olanzapine triggered my POTS and I haven't recovered since August. I'm constantly dizzy and I can barely leave the house. Ive only been to the store 5 times since then. I constantly have anxiety and panic attacks fearing I'

r/schizophrenia95411y ago

Dizziness

Fatigue

Anxiety

Got diagnosed with bipolar I today

I feel a weird sense of relief having a name to this perpetual cycle of sadness and mania. I was apprehensive at first to seek help since there would be times I'd be happy and I used to downplay my sadness as being overreactions to heartbreaks or failures. I'm excited to start my medications (lamot

r/bipolar90322y ago

How do you feel about the local pharmacists knowing about your disease?

I've lived in the same place for about 2 years and there's a pharmacy right across the street where I go to fill my prescriptions. They have low turnover so it's always the same people who see me. And of course by now they know what I have since I buy all the classic stuff: lithium, lamotrigine, que

r/bipolar731212y ago

I didn’t jump

I need to share this with someone because if I tell my family they will freak out. I am currently travelling Asia, in Vietnam. Last night a depressive episode hit me like a ton of bricks despite slow release venlafaxine, 500mg quetiapine and propanol in my system. I went to the 8th floor of my hote

r/bipolar66136y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → QUETIAPINE openFDA label JSON → QUETIAPINE FAERS adverse-event reports → QUETIAPINE ClinicalTrials.gov → completed Phase 2+ trials of QUETIAPINE

Compare With

26 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral