Question 1

What is RANOLAZINE used for?

Accepted Answer

RANOLAZINE (brand name Ranolazine) is a Antianginal indicated for 1 INDICATIONS AND USAGE Ranolazine extended-release tablet is indicated for the treatment of chronic angina. Ranolazine extended-release tablet may be used with beta-blockers, nitrates, calcium channel blockers.

Question 2

How does RANOLAZINE work?

Accepted Answer

RANOLAZINE works through the following mechanism: 12.1 Mechanism of Action The mechanism of action of ranolazine's antianginal effects has not been determined. Ranolazine has anti-ischemic and antianginal effects that do not depend upon reductions in heart rate or blood pressure. It does not affect the rate-pressure product, a measure of myocardial work, at maximal exercise. Ranolazine at therapeutic levels can inhibit the cardiac late sodium current (I Na ). However, the relationship of this inhibition to angina symptoms is uncertain. The QT prolongation effect of ranolazine on the surface electrocardiogram is the result of inhibition of I Kr , which prolongs the ventricular action potential..

Question 3

What are the most common side effects of RANOLAZINE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for RANOLAZINE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is RANOLAZINE the same as Ranolazine?

Accepted Answer

Ranolazine is a brand name for RANOLAZINE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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