Question 1

What is RASAGILINE MESYLATE used for?

Accepted Answer

RASAGILINE MESYLATE (brand name Rasagiline) is a Parkinson's Agent indicated for 1 INDICATIONS AND USAGE Rasagiline tablets are indicated for the treatment of Parkinson’s disease (PD). Rasagiline, a monoamine oxidase (MAO)-B inhibitor (MAOI), is indicated for the treatment of Parkinson’s disease (1).

Question 2

How does RASAGILINE MESYLATE work?

Accepted Answer

RASAGILINE MESYLATE works through the following mechanism: 12.1 Mechanism of Action Rasagiline is a selective, irreversible MAO-B inhibitor indicated for the treatment of idiopathic Parkinson’s disease. The results of a clinical trial designed to examine the effects of rasagiline on blood pressure when it is administered with increasing doses of tyramine indicates the functional selectivity can be incomplete when healthy subjects ingest large amounts of tyramine while receiving recommended doses of rasagiline. The selectivity for inhibiting MAO-B diminishes in a dose-related manner. MAO, a flavin-containing enzyme, is classified into two major molecular species, A and B, and is localized in mitochondrial membranes throughout the body in nerve terminals, brain, liver and intestinal mucosa. MAO regulates the metabolic degradation of catecholamines and serotonin in the CNS and peripheral tissues. MAO-B is the major form in the human brain. In ex vivo animal studies in brain, liver, and intestinal tissues, rasagiline was shown to be a potent, irre.

Question 3

What are the most common side effects of RASAGILINE MESYLATE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for RASAGILINE MESYLATE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is RASAGILINE MESYLATE the same as Rasagiline?

Accepted Answer

Rasagiline is a brand name for RASAGILINE MESYLATE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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