Question 1

What is Ribociclib used for?

Accepted Answer

Ribociclib (brand name Kisqali) is a CDK4/6 Inhibitor indicated for HR+/HER2- Breast Cancer.

Question 2

How does Ribociclib work?

Accepted Answer

Ribociclib works through the following mechanism: Selective CDK4/6 inhibitor that restores cell cycle control by blocking retinoblastoma protein phosphorylation..

Question 3

What are the most common side effects of Ribociclib?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for Ribociclib. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is Ribociclib the same as Kisqali?

Accepted Answer

Kisqali is a brand name for Ribociclib. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

Ribociclib

Mechanism of Action

Indications

Known Side Effects

Community Discussions

Primary sources

Compare With

Formulations