What is RIFAPENTINE used for?

RIFAPENTINE (brand name Priftin) is a Other indicated for recent conversion to a positive tuberculin skin test, HIV-infected patients.

What are the most common side effects of RIFAPENTINE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for RIFAPENTINE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is RIFAPENTINE the same as Priftin?

Priftin is a brand name for RIFAPENTINE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

RIFAPENTINE

Q: How does RIFAPENTINE work?

RIFAPENTINE works through the following mechanism: 12.1 Mechanism of Action Rifapentine, a cyclopentyl rifamycin, is an antimycobacterial agent [see Microbiology (12.4) ] ..

Other

Brand names: Priftin

Oral

Mechanism of Action

12.1 Mechanism of Action Rifapentine, a cyclopentyl rifamycin, is an antimycobacterial agent [see Microbiology (12.4) ] .

Indications

recent conversion to a positive tuberculin skin test

HIV-infected patients

Contraindications

• 4 CONTRAINDICATIONS Known hypersensitivity to any rifamycin. ( 4.1 ) 4.1 Hypersensitivity PRIFTIN is contraindicated in patients with a history of hypersensitivity to rifamycins.

FDA Warnings

5 WARNINGS AND PRECAUTIONS Hepatotoxicity: Monitor for symptoms of liver injury and discontinue PRIFTIN if signs or symptoms or liver injury occur
8 Clostridioides Difficile –Associated Diarrhea Clostridioides difficile –associated diarrhea (CDAD) has been reported with the use of nearly all systemic antibacterial agents, including PRIFTIN, with severity ranging from mild diarrhea to fatal colitis

Known Side Effects

11 documented side effects by frequency

Fever

>10%

Nausea

1-10%

High Blood Pressure

1-10%

Fatigue

1-10%

Vomiting

1-10%

Headache

1-10%

Rash

1-10%

Dizziness

1-10%

Shortness of Breath

1-10%

Low Blood Pressure

0.1-1%

Muscle Pain

0.1-1%

Community Discussions

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Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → RIFAPENTINE openFDA label JSON → RIFAPENTINE FAERS adverse-event reports → RIFAPENTINE ClinicalTrials.gov → completed Phase 2+ trials of RIFAPENTINE

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Formulations

Dosage Forms

Tablet

Route

Oral