What is RIZATRIPTAN used for?

RIZATRIPTAN (brand name Rizatriptan) is a Triptan (Migraine) indicated for See full prescribing information.

What are the most common side effects of RIZATRIPTAN?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for RIZATRIPTAN. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is RIZATRIPTAN the same as Rizatriptan?

Rizatriptan is a brand name for RIZATRIPTAN. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

RIZATRIPTAN

Q: How does RIZATRIPTAN work?

RIZATRIPTAN works through the following mechanism: 12.1 Mechanism of Action Rizatriptan binds with high affinity to human cloned 5-HT 1B/1D receptors. Rizatriptan presumably exerts its therapeutic effects in the treatment of migraine headache by binding to 5-HT 1B/1D receptors located on intracranial blood vessels and sensory nerves of the trigeminal system..

Triptan (Migraine)

Brand names: Rizatriptan, Maxalt

Oral

Mechanism of Action

12.1 Mechanism of Action Rizatriptan binds with high affinity to human cloned 5-HT 1B/1D receptors. Rizatriptan presumably exerts its therapeutic effects in the treatment of migraine headache by binding to 5-HT 1B/1D receptors located on intracranial blood vessels and sensory nerves of the trigeminal system.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS Rizatriptan benzoate tablets are contraindicated in patients with: • Ischemic coronary artery disease (angina pectoris
• history of myocardial infarction
• or documented silent ischemia)
• within 24 hours) of another 5-HT 1 agonist
• ergotamine-containing medication

FDA Warnings

5 WARNINGS AND PRECAUTIONS • Myocardial ischemia, myocardial infarction, and Prinzmetal's angina: Perform cardiac evaluation in patients with multiple cardiovascular risk factors ( 5
2 ) • Chest/throat/neck/jaw pain, tightness, pressure, or heaviness; Generally not associated with myocardial ischemia; Evaluate patients at high risk ( 5
There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of rizatriptan benzoate
Triptan-naïve patients who have multiple cardiovascular risk factors (e

Known Side Effects

11 documented side effects by frequency

Drug Not Working

>10%

Nausea

>10%

Headache

>10%

Fatigue

1-10%

Vomiting

1-10%

Dizziness

0.1-1%

Diarrhea

0.1-1%

Shortness of Breath

0.1-1%

Joint Pain

0.1-1%

Anxiety

0.1-1%

Excessive Sweating

0.1-1%

Community Discussions

No community discussions found for RIZATRIPTAN yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → RIZATRIPTAN openFDA label JSON → RIZATRIPTAN FAERS adverse-event reports → RIZATRIPTAN ClinicalTrials.gov → completed Phase 2+ trials of RIZATRIPTAN

Compare With

17 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral