What is ROPINIROLE used for?

ROPINIROLE (brand name ropinirole) is a Parkinson's Agent indicated for See full prescribing information.

What are the most common side effects of ROPINIROLE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for ROPINIROLE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is ROPINIROLE the same as ropinirole?

ropinirole is a brand name for ROPINIROLE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

ROPINIROLE

Q: How does ROPINIROLE work?

ROPINIROLE works through the following mechanism: 12.1 Mechanism of Action Ropinirole is a non-ergoline dopamine agonist. The precise mechanism of action of ropinirole as a treatment for Parkinson’s disease is unknown, although it is thought to be related to its ability to stimulate dopamine D 2 receptors within the caudate-putamen in the brain. The precise mechanism of action of ropinirole as a treatment for RLS is unknown, although it is thought to be related to its ability to stimulate dopamine receptors..

Parkinson's Agent

Brand names: ropinirole, Requip

Oral

Mechanism of Action

12.1 Mechanism of Action Ropinirole is a non-ergoline dopamine agonist. The precise mechanism of action of ropinirole as a treatment for Parkinson’s disease is unknown, although it is thought to be related to its ability to stimulate dopamine D 2 receptors within the caudate-putamen in the brain. The precise mechanism of action of ropinirole as a treatment for RLS is unknown, although it is thought to be related to its ability to stimulate dopamine receptors.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS Ropinirole tablets are contraindicated in patients known to have a hypersensitivity/allergic reaction (including urticaria
• angioedema
• rash
• pruritus) to ropinirole or to any of the excipients. History of hypersensitivity/allergic reaction (including urticaria
• angioedema

FDA Warnings

5 WARNINGS AND PRECAUTIONS Sudden onset of sleep and somnolence may occur ( 5
Although many of these patients reported somnolence while on ropinirole, some perceived that they had no warning signs, such as excessive drowsiness, and believed that they were alert immediately prior to the event
Before initiating treatment with ropinirole, patients should be advised of the potential to develop drowsiness and specifically asked about factors that may increase the risk with ropinirole such as concomitant sedating medications or alcohol, the presence of sleep disorders (other than RLS), and concomitant medications that increase ropinirole plasma levels (e
Patients on ropinirole should be monitored for signs and symptoms of orthostatic hypotension, especially during dose escalation, and should be informed of the risk for syncope and hypotension [ see Patient Counseling Information ( 17 )]

Known Side Effects

10 documented side effects by frequency

Drug Not Working

>10%

Falls

1-10%

Fatigue

1-10%

Nausea

1-10%

Dizziness

1-10%

Shortness of Breath

1-10%

Diarrhea

1-10%

Weakness

1-10%

Headache

1-10%

Insomnia

1-10%

Community Discussions

No community discussions found for ROPINIROLE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → ROPINIROLE openFDA label JSON → ROPINIROLE FAERS adverse-event reports → ROPINIROLE ClinicalTrials.gov → completed Phase 2+ trials of ROPINIROLE

Compare With

11 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral