Question 1

What is Saxagliptin used for?

Accepted Answer

Saxagliptin (brand name Onglyza) is a DPP-4 Inhibitor indicated for Type 2 Diabetes Mellitus.

Question 2

How does Saxagliptin work?

Accepted Answer

Saxagliptin works through the following mechanism: Inhibits DPP-4 enzyme to increase incretin levels, enhancing glucose-dependent insulin secretion and suppressing glucagon..

Question 3

What are the most common side effects of Saxagliptin?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for Saxagliptin. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is Saxagliptin the same as Onglyza?

Accepted Answer

Onglyza is a brand name for Saxagliptin. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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