How does SECNIDAZOLE work?

SECNIDAZOLE works through the following mechanism: 12.1 Mechanism of Action SOLOSEC is a nitroimidazole antimicrobial drug [see Microbiology (12.4) ]..

What are the most common side effects of SECNIDAZOLE?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for SECNIDAZOLE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is SECNIDAZOLE the same as Solosec?

Solosec is a brand name for SECNIDAZOLE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

SECNIDAZOLE

Q: What is SECNIDAZOLE used for?

SECNIDAZOLE (brand name Solosec) is a Antifungal indicated for SOLOSEC should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy..

Antifungal

Brand names: Solosec

Oral

Mechanism of Action

12.1 Mechanism of Action SOLOSEC is a nitroimidazole antimicrobial drug [see Microbiology (12.4) ].

Indications

SOLOSEC should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available

they should be considered in selecting or modifying antibacterial therapy. In the absence of such data

local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Contraindications

• 4. CONTRAINDICATIONS SOLOSEC is contraindicated: In patients who have shown hypersensitivity to secnidazole
• another nitroimidazole drug
• structurally related to secnidazole
• in patients with Cockayne syndrome [see Adverse Reactions (6.2) ] . History of hypersensitivity to secnidazole
• or other nitroimidazole derivatives. ( 4 ) Patients with Cockayne syndrome. ( 4

FDA Warnings

5 WARNINGS AND PRECAUTIONS Vulvovaginal Candidiasis: This may develop with SOLOSEC and require treatment with an antifungal agent
1 ) Potential Risk for Carcinogenicity : Carcinogenicity has been seen in mice and rats treated chronically with nitroimidazole derivatives, which are structurally related to secnidazole
It is unclear if the positive tumor findings in lifetime rodent studies indicate a risk to patients taking a single dose of SOLOSEC to treat bacterial vaginosis
2 Potential Risk for Carcinogenicity Carcinogenicity has been seen in mice and rats treated chronically with nitroimidazole derivatives which are structurally related to secnidazole

Known Side Effects

7 documented side effects by frequency

Vomiting

>10%

Nausea

>10%

Drug Not Working

1-10%

Diarrhea

1-10%

Headache

1-10%

Abdominal Pain

0.1-1%

General Unwellness

0.1-1%

Community Discussions

No community discussions found for SECNIDAZOLE yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → SECNIDAZOLE openFDA label JSON → SECNIDAZOLE FAERS adverse-event reports → SECNIDAZOLE ClinicalTrials.gov → completed Phase 2+ trials of SECNIDAZOLE

Compare With

14 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral