Question 1

What is SONIDEGIB used for?

Accepted Answer

SONIDEGIB (brand name Odomzo) is a Other indicated for 1 INDICATIONS AND USAGE ODOMZO (sonidegib) is indicated for the treatment of adult patients with locally advanced basal cell carcinoma (BCC) that has recurred following surgery or radiation therapy, or those who are not candidates for surgery or radiation therapy. ( 1 ).

Question 2

How does SONIDEGIB work?

Accepted Answer

SONIDEGIB works through the following mechanism: 12.1 Mechanism of Action Sonidegib is an inhibitor of the Hh pathway. Sonidegib binds to and inhibits Smoothened, a transmembrane protein involved in Hh signal transduction..

Question 3

What are the most common side effects of SONIDEGIB?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for SONIDEGIB. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is SONIDEGIB the same as Odomzo?

Accepted Answer

Odomzo is a brand name for SONIDEGIB. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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