Question 1

What is TAMOXIFEN CITRATE used for?

Accepted Answer

TAMOXIFEN CITRATE (brand name SOLTAMOX) is a SERM indicated for following breast surgery and radiation.

Question 2

How does TAMOXIFEN CITRATE work?

Accepted Answer

TAMOXIFEN CITRATE works through the following mechanism: 12.1 Mechanism of Action Tamoxifen is an estrogen agonist/antagonist. Tamoxifen competes with estrogen for binding to the estrogen receptor, which can result in a decrease in estrogen receptor signaling-dependent growth in breast tissue. Tamoxifen has demonstrated antitumor activity against human breast cancer cell lines xenografted in mice. The drug has been shown to inhibit the induction of rat mammary carcinoma induced by dimethylbenzanthracene (DMBA) and to cause the regression of already established DMBA-induced tumors..

Question 3

What are the most common side effects of TAMOXIFEN CITRATE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for TAMOXIFEN CITRATE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is TAMOXIFEN CITRATE the same as SOLTAMOX?

Accepted Answer

SOLTAMOX is a brand name for TAMOXIFEN CITRATE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

TAMOXIFEN CITRATE

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