Question 1

What is TRIFAROTENE used for?

Accepted Answer

TRIFAROTENE (brand name AKLIEF) is a Other indicated for See full prescribing information.

Question 2

How does TRIFAROTENE work?

Accepted Answer

TRIFAROTENE works through the following mechanism: 12.1 Mechanism of Action Trifarotene is an agonist of retinoic acid receptors (RAR), with particular activity at the gamma subtype of RAR. Stimulation of RAR results in modulation of target genes which are associated with various processes, including cell differentiation and mediation of inflammation. The exact process by which trifarotene ameliorates acne is unknown..

Question 3

What are the most common side effects of TRIFAROTENE?

Accepted Answer

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for TRIFAROTENE. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Question 4

Is TRIFAROTENE the same as AKLIEF?

Accepted Answer

AKLIEF is a brand name for TRIFAROTENE. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

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